Eagles vs. Lions Point Spread: NFL Week 1 Odds, Prediction

Daniel Coyle | Updated Sep 08, 2022

Two teams looking to make substantial gains this clash on Sunday, as the Detroit Lions host the Philadelphia Eagles in NFL Week 1 action.

September 11, 2022, 1:00 PM ET
Ford Field
Pointspread -6 -114
Moneyline -261
Over / Under o +48.5


Betting Action


Pointspread +6 -106
Moneyline +216
Over / Under u +48.5


Betting Action


The Eagles look to take the next step after surprisingly seizing a wild card berth in last year’s NFL playoffs, and have also emerged as narrow +125 season-opening favourites to finish atop the NFC East standings this time around. A Week 18 victory over Green Bay denied the Lions a last-place finish in the NFL standings and the top pick in the 2022 NFL Draft. However, that victory leaves Detroit riding a three-game win streak on home turf to open the new season.

The Eagles have held steady since opening as 4-point favourites, but with 73% of sports bettors backing them, Philadelphia have improved to a -115 bet to cover that spread. The total has made steady upward progress since opening at 46.5, and is currently pegged at 48.5. However, it is the UNDER that has garnered 56% of the betting action.

NFL Week 1 Point Spread and Betting Analysis

Sunday afternoon’s matchup at Ford Field marks the second time in as many years that the Lions have welcomed the Eagles to town. Philadelphia romped to a 44-6 victory as 3-point chalk in that Week 8 win to claim their first win in the Motor City since 2010, and just its second victory in six dates with the Lions. Detroit has also held the edge at the sportsbooks in head-to-head action, covering in five of seven meetings with Philly. Recent clashes between these teams have been high scoring, with the total reaching 49 or higher in seven of their past eight, fueling an 8-0-0 run for the OVER.

While the Lions struggled on the scoreboard last season, they paid out regularly at the sportsbooks. The team saw five of their 13 defeats come by four or fewer points, and have gone unbeaten against the spread in four home dates since suffering that dirty beating from the Eagles last October. A 6-3-0 road record played a key role in the Eagles’ return to playoff contention last season. That includes a 3-1-0 run as road chalk, during which they limited a opponents to just 13.3 points per game.

Philadelphia Eagles

The pressure will be on quarterback Jalen Hurts to quickly establish himself as an elite quarterback this season. Now entering his third NFL campaign, Hurts racked up 3144 passing yards last season, but failed to reach the end zone with consistency. The 24-year-old racked up seven touchdown passes through Week 4, and saw nine of his 16 scoring tosses come on the road. However, he failed to throw a scoring pass in three of the team’s final five regular season outings, and didn’t find the end zone until well into garbage time in the Eagles’ crushing 31-15 loss to Tampa Bay on Wild Card Weekend. However, the addition of AJ Brown now provides Hurts with a wealth of downfield targets, as does the availability to start the season of both Jordan Mailata and Lane Johnson on what many observers consider to be among the toughest offensive lines in the NFL.

Detroit Lions

To say that Jared Goff has a lot to prove heading into the new NFL season is a massive understatement. Forced to watch the Los Angeles Rams team that dumped him to the curb go on to win Super Bowl 56 with the man who replaced him was a bitter pill for Goff to swallow. Now fully recovered from an injury that limited him to just 14 games last season, Goff aims to finish on a strong finish to 2021, which he closed out by tossing for 11 touchdowns over his final five appearances. With the Lions bolstering their receiving corps with the addition of Amon-Ra St. Brown, there is good reason for optimism. However, concerns about the offensive line have emerged since the team placed guard Halapoulivaati Vaitai on the IR earlier this week.

NFL Prediction: Who Will Win Eagles vs. Lions?