Colts vs. Titans Point Spread: NFL Week 17 Odds, Prediction
Both teams set up this winner-take-all tilt with pivotal Week 16 victories, as the Titans upended Washington 25-16 while the Colts pulled out a 28-27 triumph over the New York Giants.
NFL Point Spread and Betting Analysis
The status of Titans quarterback Marcus Mariota will have the biggest impact on betting ahead of this pivotal AFC South encounter. Mariota suffered a stinger in the win over Washington but felt better Monday and will be monitored throughout the week. The Colts have dominated the head-to-head matchup from a covers perspective, having gone a red-hot 11-3 ATS in the last four meetings – but the home team has covered five of the past seven.
The Colts have made under bettors quite rich heading into the final week of the season. Indy is 5-1 to the under in its previous six games and has converted eight consecutive unders vs. teams with winning records. The Titans’ total trends are a little more difficult to pin down. Tennessee is 4-1 O/U in its past five games overall but has been a much stronger under play within the division, going below the number in six of eight games vs. AFC South foes.
Indianapolis Colts
Mariota’s status is the big talking point entering the week, but the Colts have injury concerns of their own. Sensational tight end Eric Ebron is in the concussion protocol after being knocked out of Sunday’s victory over the Giants; he’ll need to be cleared in order to play. It’s a potentially major blow to a Colts offence that revolves around tight end play; the TE quartet of Ebron, Jack Doyle, Mo-Alie Cox and Eric Swoope has 19 of Indy’s 36 receiving scores.
Tennessee Titans
You won’t find many superior home cover options to the Titans, who are 13-5-1 ATS in their past 19 games at Nissan Stadium. And extending that streak – with or without Mariota – will be a serious challenge if the Titans don’t get more heroics from Derrick Henry. The 24-year-old running back has erupted for 492 yards and seven scores over his past three games. The Colts have limited foes to 3.8 yards per carry, fourth-fewest in the NFL.


