TNF Colts vs. Titans Point Spread: NFL Week 10 Odds, Prediction

Payton Matthews | Updated Nov 09, 2020

Derrick Henry, Titans, 2019

Week 10 kicks off in Tennessee Thursday night. The Titans open up as slight favourites against the Colts.

November 12, 2020, 8:20 PM ET
Nissan Stadium
Pointspread 0 -104
Moneyline +105
Over / Under o +49


Betting Action


Pointspread 0 -116
Moneyline -120
Over / Under u +49


Betting Action


One of the marquee matchups of the NFL’s Week 10 so happens to be Thursday night as the Indianapolis Colts visit the Tennessee Titans in a very important AFC South showdown. The Titans opened as 2.5-point favorites on the NFL odds with a total of 49.5.

NFL Point Spread and Betting Analysis

Houston has dominated the AFC South over the past five seasons by winning it four times, while the Jacksonville Jaguars interrupted that stretch in 2017. There’s no chance either of those bad teams are winning the division in 2020.

Indianapolis is looking for its first division crown since 2014; the Colts reached the AFC title game that season and lost the “Deflategate” matchup vs. the New England Patriots. Tennessee hasn’t won the South since 2008. These teams play again on Nov. 29 in Indianapolis, so if one team sweeps the other that club most likely claims the South. The remaining schedule overall seems to favour Indy.

Last year, the teams split with each winning on the road and the losing team scoring 17 points in each. The one in Nashville was Week 2 and a 19-17 Colts victory. Jacoby Brissett threw the game-winning TD pass with under five minutes left. He’s now the backup behind Philip Rivers. Current Titans QB Ryan Tannehill was the backup in that game but is now the undisputed starter and was under centre for the Titans’ Week 13 31-17 victory in Indianapolis. Derrick Henry was a monster in that one with 149 yards rushing and a TD.

The favourite is 6-1 against the spread in the past seven meetings.

Indianapolis Colts

The Colts had a two-game winning streak snapped Sunday in a 24-10 home loss to the Baltimore Ravens. If there’s one clear flaw on Indy, it’s Rivers. He’s a future Hall of Famer, most likely, but he’s just not very good these day as he keeps turning the ball over. He didn’t have a TD pass and threw a pick in the loss. That pick was originally called an incompletion but was changed to an interception upon review. That would eventually lead to the winning touchdown. Top Colts wideout TY Hilton didn’t play due to a groin injury. Obviously, it will be tough for him to get back on a short week.

Tennessee Titans

The Titans snapped a two-game slide and took over sole possession of first in the division with a 24-17 home win over Chicago on Sunday. Tennessee had just 228 yards of offence and 11 first downs, but the Titans’ defence held the Bears to 2-for-15 on third down and forced two turnovers. One was a Desmond King 63-yard fumble return for a touchdown. He was just acquired from the Chargers ahead of last Tuesday’s Trade Deadline. He didn’t even meet his new teammates until Saturday as King had to clear COVID-19 protocols. AJ Brown had a TD catch for the fifth straight game, making him the third player to do that this season so far. That streak is also tied for third-longest in team history. Top defensive end Jadeveon Clowney missed the game with a knee injury. He might have to go on injured reserve.

Who Will Win Colts vs. Titans?