Colts vs. Jaguars Week 8 Betting Odds, Prediction and Picks: Colts Enter After Major Roster Shakeup
Following a mid-week purge, the Indianapolis Colts visit the Jacksonville Jaguars on Sunday in an important AFC South matchup.
Indianapolis dropped to 2-5 following a 16-10 loss to Minnesota, its third consecutive defeat.
The Colts subsequently traded All-Pro guard Quenton Nelson to Seattle and defensive tackle DeForest Buckner to San Francisco, signalling a significant roster overhaul ahead of the November 10 trade deadline.
Jacksonville enters at 4-2 following its bye week, looking to rebound from a 34-31 loss to Houston in London.
Colts vs. Jaguars Kickoff, Weather, TV, Streaming Info
In Canada, Colts vs. Jaguars kicks off Sunday at 1 p.m. ET and can be streamed nationwide on DAZN through NFL Game Pass.
Early forecasts suggest possible rain and breezy conditions, which could affect passing and kicking.
NFL Betting Odds, Point Spread, Predictions
Jacksonville is a 7.5-point favourite at -112, with a -385 money line. Indianapolis is +7.5 at -108 and +295 outright. The total is 46.5 points, with the Over and Under both at -110.
Spread
Indianapolis is 4-3 against the spread, while Jacksonville is 4-2 ATS.
The Jaguars have won five of the last six meetings, including both matchups last season. Jacksonville has allowed just 17.3 points per game, compared with Indianapolis’ 25.7.
Check out all our weekly NFL predictions here.
NFL Player Odds and Props
Jonathan Taylor Under 73.5 Rushing Yards (-116)
Taylor leads Indianapolis with 587 rushing yards and eight touchdowns.
However, Jacksonville has allowed just 72.2 rushing yards per game, the NFL’s best mark.The Jaguars’ defensive front presents a difficult matchup, particularly if Indianapolis falls behind early.
Daniel Jones Under 191.5 Passing Yards (-116)
Jones has thrown for 1,398 yards, four touchdowns and seven interceptions this season.
Indianapolis managed just 10 points against Minnesota, continuing its offensive struggles. Jacksonville’s ability to generate turnovers makes another difficult afternoon possible.
Trevor Lawrence Over 249.5 Passing Yards (-116)
Lawrence has thrown for 1,480 yards and 14 touchdowns through six games. He threw for 331 yards against Philadelphia before adding 306 against Houston.
Indianapolis has struggled to generate takeaways, creating opportunities for Jacksonville’s passing attack.
Parker Washington Over 68.5 Receiving Yards (-116)
Washington leads Jacksonville with 416 receiving yards and four touchdowns. He has developed into a dependable target in Lawrence’s improving passing offence.
Indianapolis could struggle to contain Jacksonville’s receivers if its secondary remains short-handed.
Indianapolis Colts
The departures of Nelson and Buckner leave significant holes on both sides of the football.
Nelson’s absence could make it more difficult for Jonathan Taylor to find running room against Jacksonville’s league-leading rushing defence.
Defensively, the Colts face additional concerns. Cornerback Sauce Gardner is recovering from a calf strain, while Cam Taylor-Britt is on injured reserve. Tight end Tyler Warren is also battling a groin injury, and receiver Alec Pierce remains on injured reserve.
Jacksonville Jaguars
Lawrence has thrown six touchdowns across his last two outings, including four against Houston. Washington provides a reliable downfield option, while running back Bhayshul Tuten has accumulated 388 rushing yards.
Jacksonville’s defence has been particularly effective against the run, forcing opponents to rely on passing. However, Houston scored 34 points in the Jaguars’ most recent outing, exposing vulnerabilities.
The Jaguars have seven interceptions and a plus-five turnover differential, giving them a significant advantage over Indianapolis. A strong defensive performance should help Jacksonville control the ball and secure another divisional win.
Jacksonville also has injury concerns, with starting offensive tackle Anton Harrison out for the season after a torn ACL. Safety Antonio Johnson and cornerback Montaric Brown are also dealing with injuries, leaving questions about the Jaguars’ secondary.
IND
JAC