Buccaneers vs. Eagles Point Spread: NFL Week 6 Odds, Prediction

Payton Matthews | Updated Oct 12, 2021

It’s another prime-time game for Tom Brady and the defending Super Bowl champion Tampa Bay Buccaneers as they visit the struggling Philadelphia Eagles to kick off NFL Week 6 on Thursday night.

Tampa Bay
October 14, 2021, 8:20 PM ET
Lincoln Financial Field
Pointspread -7 -110
Moneyline -325
Over / Under o +53


Betting Action


Pointspread +7 -110
Moneyline +263
Over / Under u +53


Betting Action


The Bucs are 7-point favourites to win on the NFL odds, with a total of 52.0 points.

NFL Point Spread and Betting Analysis

Teams normally only get one Thursday game per season unless they play on Thanksgiving or in the Kickoff Game – Tampa Bay did play in the latter on Thursday, Sept. 9, and rallied to beat Dallas. This will be the Bucs’ last Thursday game of the year and the Eagles’ one and only. Tampa Bay will be in prime-time plenty the rest of the way, though. Philly doesn’t have another prime-time game scheduled, but a Sunday night flex could happen.

You can’t find two quarterbacks more different than the Bucs’ Tom Brady, who is as stationary as they come, and the Eagles’ Jalen Hurts, who is one of the league’s top running QBs. The jury is still out on Hurts as to whether he will be Philly’s long-term QB.

Philadelphia is 10-9 all-time vs. Tampa Bay including playoffs. The teams last met in 2018 in Tampa and the Bucs won 27-21. The starting quarterbacks that day? Ryan Fitzpatrick for the Bucs (now with Washington) and Nick Foles for the Eagles (now third string in Chicago). Foles, of course, led an Eagles upset of Brady’s New England Patriots in Super Bowl LII following the 2017 season.

The underdog is 6-2 against the spread in the past eight meetings.

Tampa Bay Buccaneers

Tampa Bay won its second game in a row Sunday, 45-17, over the terrible Miami Dolphins. Brady, only the greatest QB of all time, did something he never had previously: Throw for at least 400 yards (411) and five TDs (five) in the same game. That’s hard to believe. Antonio Brown caught seven passes for 124 yards and two scores and became the fastest player in history to reach 900 career receptions. Fellow wideout Mike Evans caught six balls for 113 yards and two scores. Star tight end Rob Gronkowski sat out a second straight game with fractured ribs. Highly doubt he plays here.

Safety Antoine Winfield Jr. missed Week 5 in concussion protocol but could return. Cornerback Jamel Dean returned after missing one injured. Pass-rusher Jason Pierre-Paul had missed two in a row but also played. Brady was seen with a wrap on his hand afterward due to a thumb issue but is fully expected to play Thursday. The Bucs are 1-6 ATS in their past seven Thursday games.

Philadelphia Eagles

Philadelphia was a field-goal underdog Sunday at Carolina but snapped a three-game losing streak with a 21-18 victory. Hurts wasn’t great throwing the ball but rushed for two touchdowns. He joined Randall Cunningham as the only Eagles quarterbacks with multiple two-TD rushing games. Philly only had 273 yards but also allowed just 267 and picked off Sam Darnold three times (two by Pro Bowl cornerback Darius Slay).

TJ Edwards blocked a Carolina punt that led to the Eagles’ game-winning touchdown with 2:38 left. The team then also had a two-point conversion. Pro Bowl right tackle Lane Johnson missed the game for a personal matter and it’s not clear if he’ll play Thursday. The Eagles are 5-0 ATS in their past five as home dogs.

NFL Prediction: Who Will Win Buccaneers vs. Eagles?

NFL Predictions