Bengals vs. Bills Point Spread: NFL Week 14 Odds, Prediction
Week 14 of the 2025 NFL season includes an AFC showdown between the Cincinnati Bengals and Buffalo Bills. Because they play in the moribund AFC North, the Bengals are not entirely eliminated from playoff contention despite being 4-8. The Bills are a decent 8-4, but find themselves well behind New England in the AFC East.
The all-time head-to-head series is tied up at 17-17. Cincinnati has won three of the last four encounters dating back to 2017 and six of the last eight dating back to 2011. They most recently faced each other during the 2023 regular season, when the Bengals prevailed 24-18 at home.
https://tally.site/odds/nfl/2025-26-week-14?format=american&odds-by=sports-interaction&type=games
NFL Point Spread and Betting Analysis
Cincinnati is 4-7 against the spread in its last 11 contests dating back to the 2024 campaign. Buffalo is also 4-11 ATS in its last 11 games, and it is 0-4 ATS in the last four head-to-head matchups. As for the over/under, the under is 3-0 in the Bengals’ last three overall, 6-2 in the Bills’ last eight and 5-0 in the last five head-to-head.
The NFL odds board has the Bills set as 5.5-point favourites.
In addition to the more traditional lines, the first-quarter spread is -0.5 in the Bills’ favour and the first-half spread is -3.5. The first-quarter over/under is 9.5; the first-half over/under is 26.5. Both Josh Allen and James Cook of the Bills are -200 to score a TD, while Ja’Marr Chase at -130 is the most likely anytime touchdown scorer for the Bengals.
Cincinnati Bengals
Quarterback Joe Burrow has returned for the Bengals, and just like that their offence was back in business on Thanksgiving. Burrow, who had not played since Week 2 because of a foot injury, threw for 246 yards, two touchdowns and no interceptions while leading his team to a 32-14 road upset of Baltimore. Star receiver Ja’Marr instantly enjoyed one of his most productive outings of the season, catching seven of 14 targets for 110 yards.
The concern for Cincinnati, of course, is on the defensive side of the ball. It ranks dead last in the NFL in total defence (410.0 yards per game allowed), last in scoring (31.2 points allowed), last in passing and second-to-last in rushing. Even the defence, however, seemed to be invigorated by Burrow’s return against the Ravens.
Buffalo Bills
Buffalo has struggled a bit over the past two months, which is why it is looking up at New England in the AFC East. The Bills are just 4-4 in their last eight games since beginning the season 4-0. Surprisingly, offence has been the culprit more often than not. In their four losses, Josh Allen has produced 20, 14, 13 and 19 points.
On the bright side, this should be a fantastic matchup for the home team – and especially for running back James Cook against a Cincinnati defense that is surrendering 153.3 rushing yards per game on 5.1 yards per carry. Cook has delivered a whopping seven 100-yard performances on the ground in 2025, including in each of the past two contests.
Who Will Win Bengals vs. Bills?
Cincinnati impressed against Baltimore in Week 13, but the Ravens (6-6) have been one of the most disappointing teams in the league this year. Buffalo will likely be a more difficult proposition, especially at Orchard Park. It’s hard to see the Bengals’ defence doing much to contain arguably the NFL’s best QB and reigning MVP in Allen. Let’s go with the Bills to win 31-24.
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BUF