49ers vs. Chargers Prediction, Odds & Stats - August 20, 2026

Scoreboard	1	2	3	4	Odds
San Francisco 49ers 7-1	0	20	7	14	+0
Los Angeles Chargers 0-8	0	3	6	8

Date	Result	Competition
11/08/26	Las Vegas Raiders LV ( 4-5 ) San Francisco 49ers SF ( 7-1 ) 17 - 38	AFC West
11/08/26	Houston Texans HOU ( 3-5 ) L.A. Chargers Chargers LAC ( 0-8 ) 44 - 22	AFC South
11/01/26	L.A. Chargers Chargers LAC ( 0-8 ) L.A. Rams Rams LAR ( 5-4 ) 9 - 24	AFC West

San Francisco 49ers SF L.A. Chargers Chargers LAC

	Stat
0	Games Won	1
1	Games Lost	0
7-1	Last 10	0-8
0-0	W L Streak	0-0
1-0	Against The Spread	1-0
0	Money	0
0-0	Home	0-0
0-0	Away	0-0
0-1	Total	0-1

date	home-away	ats	o/u	LAC:Total Net Yards	LAC:Net Rushing Yards	LAC:Passing Yards	SF:Total Net Yards	SF:Net Rushing Yards	SF:Passing Yards
08/20/2026	LAC 17 - SF 41	SF +1	Over 39.5	229	68	161	321	146	175
08/23/2025	SF 30 - LAC 23	SF +2.5	Over 37.5	321	82	239	238	83	155
08/25/2023	SF 12 - LAC 23	LAC +6	Under 37.5	305	267	38	310	125	185
11/13/2022	SF 22 - LAC 16	LAC +6.5	Under 45.5	238	51	187	387	157	230
08/22/2021	LAC 10 - SF 15	LAC +2.5	Under 33.5	281	148	133	162	53	109
08/29/2019	SF 24 - LAC 27	LAC +5.5	Over 34	343	190	153	285	163	122
09/30/2018	LAC 29 - SF 27	SF +10	Over 47	364	76	288	368	126	242
08/30/2018	SF 21 - LAC 23	LAC +3.5	Over 35	192	138	54	226	93	133
08/31/2017	SF 23 - LAC 13	SF -2.5	Under 37.5	304	116	188	266	201	65

date	score	ats	o/u	Total Net Yards	Net Rushing Yards	Passing Yards
11/08/2026	SF 38 - LV 17	W -8.5	Over 52	240	24	216
10/25/2026	ATL 29 - SF 20	L -4.5	Under 49.5	411	123	288
10/19/2026	SF 23 - WAS 17	L -7.5	Under 52	314	53	261
10/11/2026	SEA 29 - SF 32	W +3	Over 47	269	94	175
10/04/2026	SF 24 - DEN 14	W -2.5	Under 46	296	82	214
09/27/2026	SF 36 - ARI 30	L -8.5	Over 48	365	93	272
09/20/2026	SF 35 - MIA 13	W -10.5	Over 46	284	102	182
09/10/2026	LAR 7 - SF 27	W +2.5	Under 48.5	379	174	205
08/27/2026	LV 12 - SF 18	W +1	Under 38.5	281	146	135
08/20/2026	LAC 17 - SF 41	W +1	Over 39.5	321	146	175

date	score	ats	o/u	Total Net Yards	Net Rushing Yards	Passing Yards
11/08/2026	LAC 22 - HOU 44	L +3.5	Over 40.5	315	138	177
11/01/2026	LAR 24 - LAC 9	L +6.5	Under 45.5	281	129	152
10/18/2026	KC 22 - LAC 6	L +7.5	Under 41.5	422	150	272
10/11/2026	LAC 17 - DEN 23	L +3.5	Under 42	237	155	82
10/04/2026	SEA 30 - LAC 23	L +3	Over 45.5	286	138	148
09/27/2026	BUF 24 - LAC 16	L +7	Under 50.5	350	176	174
09/20/2026	LAC 14 - LV 26	L -9	Under 43	310	127	183
09/13/2026	LAC 14 - ARI 26	L -10.5	Under 46.5	268	81	187
08/27/2026	LAC 18 - LAR 20	L -2.5	Under 39.5	394	204	190
08/20/2026	LAC 17 - SF 41	L -1	Over 39.5	229	68	161

San Francisco 49ers SF

	Season stats	rank
Total Yards	291.9	3
Passing Yards	211	8
Rushing Yards	80.88	2
Points Scored	19.5	6
Field Goal %	0.89	23

L.A. Chargers Chargers LAC

	Season stats	rank
Total Yards	343.3	20
Passing Yards	221.25	15
Rushing Yards	122	21
Points Scored	27.38	29
Field Goal %	0.85	15

San Francisco 49ers SF

	Season stats	rank
Total Yards	376.8	6
Passing Yards	241.5	11
Rushing Yards	135.25	7
Points Scored	29.38	3
Field Goal %	0.7	29

L.A. Chargers Chargers LAC

	Season stats	rank
Total Yards	291.6	26
Passing Yards	177.13	26
Rushing Yards	114.5	16
Points Scored	15.13	32
Field Goal %	0.88	17

San Francisco 49ers SF

player (position)	status		ats*current	o/u*	notes
Trent Williams (OT)	Ques Sun	Shoulder - 12 / 11 / 26	1-0	1-0	Details
Dre Greenlaw (LB)	Ques Sun	Knee - 12 / 11 / 26	1-0	1-0	Details
Gracen Halton (DT)	Out indefinitely	Ankle - 11 / 11 / 26	1-0	1-0	Details
KhaDarel Hodge (DB)	Ques Nov 8	Knee - 01 / 11 / 26	1-1	1-1	Details
Christian McCaffrey (RB)	Ques Nov 8	Hamstring - 27 / 10 / 26	1-1	1-1	Details
Deebo Samuel Sr. (WR)	Ques Nov. 15	Hamstring - 27 / 10 / 26	1-1	1-1	Details
Garret Wallow (LB)	Ques Nov. 15	Hamstring - 20 / 10 / 26	2-2	2-2	Details
Mike Evans (WR)	Out Sun	Achilles - 20 / 10 / 26	2-2	2-2	Details
Marques Sigle (S)	Ques Nov. 15	Ankle - 06 / 10 / 26	3-2	2-3	Details
Kyle Juszczyk (FB)	Ques Mon	Knee - 06 / 10 / 26	3-2	2-3	Details

L.A. Chargers Chargers LAC

player (position)	status		ats*current	o/u*	notes
Keaton Mitchell (RB)	Ques Mon	Hip - 12 / 11 / 26	0-1	1-0	Details
Alex Harkey (G)	Ques Mon	Foot - 12 / 11 / 26	0-1	1-0	Details
Tre' Harris (WR)	Ques Mon	Shoulder - 12 / 11 / 26	0-1	1-0	Details
Kendall Williamson (S)	Ques Nov. 16	Calf - 07 / 11 / 26	0-2	1-1	Details
Deane Leonard (DB)	Ques Nov. 16	Concussion - 28 / 10 / 26	0-3	1-2	Details
Bud Dupree (LB)	Ques Sun	Neck - 19 / 10 / 26	0-3	1-2	Details
Josh Harris (LS)	Ques Nov 1	Hamstring - 19 / 10 / 26	0-3	1-2	Details
Ladd McConkey (WR)	Ques Sun	Foot - 13 / 10 / 26	0-4	1-3	Details
Tre' Harris (WR)	Ques Nov 1	Hamstring - 13 / 10 / 26	0-4	1-3	Details
Donte Jackson (CB)	Ques Sun	Hamstring - 10 / 10 / 26	0-5	2-3	Details

San Francisco 49ers SF

49ers are 2-5 ATS in their last 7 games as a road underdog of 3.5-10.0.

Over is 6-2 in 49ers last 8 games as a favorite.

Over is 5-1 in 49ers last 6 games on fieldturf.

49ers are 2-7 ATS in their last 9 games as a road underdog.

49ers are 2-5 ATS in their last 7 games as an underdog of 0.5-3.0.

L.A. Chargers Chargers LAC

Under is 5-1 in Chargers last 6 games as a home underdog of 3.5-10.0.

Chargers are 4-1 ATS in their last 5 home games.

Over is 7-1 in Chargers last 8 Thursday games.

Chargers are 5-0-1 ATS in their last 6 games as a home favorite of 3.5-10.0.

Chargers are 4-0 ATS in their last 4 games as an underdog of 0.5-3.0.

Team	Win / Loss	ATS	OU
San Francisco 49ers SF	7-1	5-3	4-4
Chicago Bears CHI	7-2	6-3	5-4
N.Y. Giants Giants NYG	5-3	5-3	4-4
Carolina Panthers CAR	3-5	3-5	4-4
Detroit Lions DET	6-2	4-4	5-3
Minnesota Vikings MIN	6-2	4-3	1-6
Green Bay Packers GB	6-3	5-2	3-6
Seattle Seahawks SEA	5-4	4-5	4-5
L.A. Rams Rams LAR	5-4	5-4	3-6
Dallas Cowboys DAL	4-5	3-3	5-3
Washington Commanders WAS	3-5	4-4	3-5
New Orleans Saints NO	3-5	3-5	5-3
Tampa Bay Buccaneers TB	3-6	3-4	5-3
Atlanta Falcons ATL	3-6	3-6	4-5
Arizona Cardinals ARI	3-6	4-5	5-4
Philadelphia Eagles PHI	2-7	1-8	2-7

Team	Win / Loss	ATS	OU
Buffalo Bills BUF	7-1	5-2	5-2
Denver Broncos DEN	7-2	7-2	4-5
Jacksonville Jaguars JAC	6-2	5-3	4-4
Pittsburgh Steelers PIT	6-2	6-2	4-4
Kansas City Chiefs KC	6-2	4-4	3-5
Cincinnati Bengals CIN	6-2	4-3	5-3
New England Patriots NE	5-4	4-4	6-3
Cleveland Browns CLE	5-4	6-3	5-4
Las Vegas Raiders LV	4-5	6-3	7-2
Baltimore Ravens BAL	4-5	2-6	5-4
Houston Texans HOU	3-5	3-5	5-3
N.Y. Jets Jets NYJ	2-7	2-5	4-5
Indianapolis Colts IND	2-7	4-4	5-4
Miami Dolphins MIA	1-7	3-4	4-4
Tennessee Titans TEN	1-7	5-3	4-4
L.A. Chargers Chargers LAC	0-8	0-8	2-6

San Francisco 49ers

Pitchers

POS	Player

Hitters

POS	Player

Los Angeles Chargers

Pitchers

POS	Player

Hitters

POS	Player

Game Statistics

321

229

Total Yards

175

161

Passing Yards

146

Rushing Yards

Touchdowns

100

Field Goal %

Turnovers

Team	Last 5 Matches
San Francisco 49ers SF ( 7-1 )	W L W W W
L.A. Chargers Chargers LAC ( 0-8 )	L L L L L

11/15/26

4:25 pm ET

San Francisco 49ers SF ( 7-1 )

Dallas Cowboys DAL ( 4-5 )

vs
Matchup

11/16/26

8:15 pm ET

L.A. Chargers Chargers LAC ( 0-8 )

Baltimore Ravens BAL ( 4-5 )

vs
Matchup

Christian McCaffrey Running Back L.A. Chargers	10	Touchdowns	3	Omarion Hampton Running Back San Francisco
Christian McCaffrey Running Back L.A. Chargers	457	Rushing	369	Omarion Hampton Running Back San Francisco
Brock Purdy Quarterback L.A. Chargers	1980	Passing	1591	Justin Herbert Quarterback San Francisco
George Kittle Tight End L.A. Chargers	38	Receiving	21	Tre' Harris Wide Receiver San Francisco
Keion White Defensive End L.A. Chargers	3.5	Sacks	3	Khalil Mack Linebacker San Francisco
Renardo Green Cornerback L.A. Chargers	4	Interceptions	2	Cam Hart Cornerback San Francisco

team	w games_won	l games_lost	t games_tied	pf points
San Francisco 49ers SF	7	1	0	235
Seattle Seahawks SEA	5	4	0	202
L.A. Rams Rams LAR	5	4	0	214
Arizona Cardinals ARI	3	6	0	178
Carolina Panthers CAR	3	5	0	199
New Orleans Saints NO	3	5	0	185
Tampa Bay Buccaneers TB	3	6	0	202
Atlanta Falcons ATL	3	6	0	188
N.Y. Giants Giants NYG	5	3	1	203
Dallas Cowboys DAL	4	5	0	246
Washington Commanders WAS	3	5	1	196
Philadelphia Eagles PHI	2	7	0	148
Chicago Bears CHI	7	2	0	241
Detroit Lions DET	6	2	0	222
Minnesota Vikings MIN	6	2	0	146
Green Bay Packers GB	6	3	0	216

Game Preview

49ers vs. Chargers Point Spread: NFL Pre-Season Week 2 Odds, Prediction

The San Francisco 49ers travel to SoFi Stadium this Thursday night to take on the Los Angeles Chargers in both teams' second preseason contest.

Team	Win / Loss	ATS	OU
San Francisco 49ers SF	7-1	5-3	4-4
Chicago Bears CHI	7-2	6-3	5-4
N.Y. Giants Giants NYG	5-3	5-3	4-4
Carolina Panthers CAR	3-5	3-5	4-4
Detroit Lions DET	6-2	4-4	5-3
Minnesota Vikings MIN	6-2	4-3	1-6
Green Bay Packers GB	6-3	5-2	3-6
Seattle Seahawks SEA	5-4	4-5	4-5
L.A. Rams Rams LAR	5-4	5-4	3-6
Dallas Cowboys DAL	4-5	3-3	5-3
Washington Commanders WAS	3-5	4-4	3-5
New Orleans Saints NO	3-5	3-5	5-3
Tampa Bay Buccaneers TB	3-6	3-4	5-3
Atlanta Falcons ATL	3-6	3-6	4-5
Arizona Cardinals ARI	3-6	4-5	5-4
Philadelphia Eagles PHI	2-7	1-8	2-7

Team	Win / Loss	ATS	OU
Buffalo Bills BUF	7-1	5-2	5-2
Denver Broncos DEN	7-2	7-2	4-5
Jacksonville Jaguars JAC	6-2	5-3	4-4
Pittsburgh Steelers PIT	6-2	6-2	4-4
Kansas City Chiefs KC	6-2	4-4	3-5
Cincinnati Bengals CIN	6-2	4-3	5-3
New England Patriots NE	5-4	4-4	6-3
Cleveland Browns CLE	5-4	6-3	5-4
Las Vegas Raiders LV	4-5	6-3	7-2
Baltimore Ravens BAL	4-5	2-6	5-4
Houston Texans HOU	3-5	3-5	5-3
N.Y. Jets Jets NYJ	2-7	2-5	4-5
Indianapolis Colts IND	2-7	4-4	5-4
Miami Dolphins MIA	1-7	3-4	4-4
Tennessee Titans TEN	1-7	5-3	4-4
L.A. Chargers Chargers LAC	0-8	0-8	2-6

49ers vs. Chargers Prediction, Odds & Stats August 20, 2026

Final Score

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Chargers

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Christian McCaffrey

Omarion Hampton

Christian McCaffrey

Omarion Hampton

Brock Purdy

Justin Herbert

George Kittle

Tre' Harris

Keion White

Khalil Mack

Renardo Green

Cam Hart

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49ers vs. Chargers Point Spread: NFL Pre-Season Week 2 Odds, Prediction

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