49ers vs. Chargers Prediction, Odds & Stats - August 20, 2026

Scoreboard	1	2	3	4	Odds
San Francisco 49ers 3-0	0	20	7	14	+0
Los Angeles Chargers 0-3	0	3	6	8

Date	Result	Competition
09/27/26	Arizona Cardinals ARI ( 1-2 ) San Francisco 49ers SF ( 3-0 ) 30 - 36	NFC West
09/27/26	L.A. Chargers Chargers LAC ( 0-3 ) Buffalo Bills BUF ( 3-0 ) 16 - 24	AFC West
09/20/26	Miami Dolphins MIA ( 0-3 ) San Francisco 49ers SF ( 3-0 ) 13 - 35	AFC East

San Francisco 49ers SF L.A. Chargers Chargers LAC

	Stat
0	Games Won	1
1	Games Lost	0
3-0	Last 10	0-3
0-0	W L Streak	0-0
1-0	Against The Spread	1-0
0	Money	0
0-0	Home	0-0
0-0	Away	0-0
0-1	Total	0-1

date	home-away	ats	o/u	LAC:Total Net Yards	LAC:Net Rushing Yards	LAC:Passing Yards	SF:Total Net Yards	SF:Net Rushing Yards	SF:Passing Yards
08/20/2026	LAC 17 - SF 41	SF +1	Over 39.5	229	68	161	321	146	175
08/23/2025	SF 30 - LAC 23	SF +2.5	Over 37.5	321	82	239	238	83	155
08/25/2023	SF 12 - LAC 23	LAC +6	Under 37.5	305	267	38	310	125	185
11/13/2022	SF 22 - LAC 16	LAC +6.5	Under 45.5	238	51	187	387	157	230
08/22/2021	LAC 10 - SF 15	LAC +2.5	Under 33.5	281	148	133	162	53	109
08/29/2019	SF 24 - LAC 27	LAC +5.5	Over 34	343	190	153	285	163	122
09/30/2018	LAC 29 - SF 27	SF +10	Over 47	364	76	288	368	126	242
08/30/2018	SF 21 - LAC 23	LAC +3.5	Over 35	192	138	54	226	93	133
08/31/2017	SF 23 - LAC 13	SF -2.5	Under 37.5	304	116	188	266	201	65

date	score	ats	o/u	Total Net Yards	Net Rushing Yards	Passing Yards
09/27/2026	SF 36 - ARI 30	L -8.5	Over 48	365	93	272
09/20/2026	SF 35 - MIA 13	W -10.5	Over 46	284	102	182
09/10/2026	LAR 7 - SF 27	W +2.5	Under 48.5	379	174	205
08/27/2026	LV 12 - SF 18	W +1	Under 38.5	281	146	135
08/20/2026	LAC 17 - SF 41	W +1	Over 39.5	321	146	175
08/13/2026	SF 13 - TEN 19	L +2	Under 38.5	279	167	112

date	score	ats	o/u	Total Net Yards	Net Rushing Yards	Passing Yards
09/27/2026	BUF 24 - LAC 16	L +7	Under 50.5	350	176	174
09/20/2026	LAC 14 - LV 26	L -9	Under 43	310	127	183
09/13/2026	LAC 14 - ARI 26	L -10.5	Under 46.5	268	81	187
08/27/2026	LAC 18 - LAR 20	L -2.5	Under 39.5	394	204	190
08/20/2026	LAC 17 - SF 41	L -1	Over 39.5	229	68	161
08/13/2026	HOU 7 - LAC 27	W +1.5	Under 38	209	111	98

San Francisco 49ers SF

	Season stats	rank
Total Yards	313	9
Passing Yards	207.33	15
Rushing Yards	105.67	15
Points Scored	16.67	3
Field Goal %	0.83	14

L.A. Chargers Chargers LAC

	Season stats	rank
Total Yards	349.3	23
Passing Yards	233	21
Rushing Yards	116.33	19
Points Scored	25.33	20
Field Goal %	0.86	16

San Francisco 49ers SF

	Season stats	rank
Total Yards	399.3	5
Passing Yards	263	7
Rushing Yards	136.33	6
Points Scored	32.67	2
Field Goal %	0.75	22

L.A. Chargers Chargers LAC

	Season stats	rank
Total Yards	308.7	20
Passing Yards	195.67	20
Rushing Yards	113	12
Points Scored	14.67	29
Field Goal %	0.6	32

San Francisco 49ers SF

player (position)	status		ats*current	o/u*	notes
Nick Bosa (DL)	Ques Sun	Calf - 26 / 09 / 26	1-1	2-0	Details
C.J. West (DT)	Out indefinitely	Undisclosed - 23 / 09 / 26	1-1	2-0	Details
James Thompson Jr. (DL)	Out Indefinitey	Ankle - 22 / 09 / 26	1-1	2-0	Details
Nick Zakelj (OL)	Out Indefinitey	Undisclosed - 22 / 09 / 26	1-1	2-0	Details
Jack Jones (CB)	Ques Sept,27th	Foot - 22 / 09 / 26	1-1	2-0	Details
Mike Evans (WR)	Ques Sept. 27th	Hip - 22 / 09 / 26	1-1	2-0	Details
Andrew Farmer II (DL)	Out Indefinitey	Back - 22 / 09 / 26	1-1	2-0	Details
Mikail Kamara (DL)	Out Indefinitey	Knee - 22 / 09 / 26	1-1	2-0	Details
Mykel Williams (DL)	Out Indefinitey	Knee - 22 / 09 / 26	1-1	2-0	Details
Demarcus Robinson (WR)	Ques Sun	Ankle - 21 / 09 / 26	1-1	2-0	Details

L.A. Chargers Chargers LAC

player (position)	status		ats*current	o/u*	notes
Trey Lance (QB)	Ques Sun	Groin - 26 / 09 / 26	0-2	0-2	Details
Cole Strange (G)	Ques Sun	Pectoral - 24 / 09 / 26	0-2	0-2	Details
Tuli Tuipulotu (LB)	Ques Sun	Hamstring - 24 / 09 / 26	0-2	0-2	Details
Rodney Shelley (CB)	Ques Sun	Hamstring - 24 / 09 / 26	0-2	0-2	Details
Brenen Thompson (WR)	Ques Sun	Quadricep - 23 / 09 / 26	0-2	0-2	Details
Kayode Awosika (G)	Ques Sun	Leg - 22 / 09 / 26	0-2	0-2	Details
Elijah Molden (DB)	Ques Sun	Hamstring - 22 / 09 / 26	0-2	0-2	Details
Isaiah World (OT)	Out indefinitely	Knee - 22 / 09 / 26	0-2	0-2	Details
Derwin James Jr. (S)	Ques Sun	Finger - 22 / 09 / 26	0-2	0-2	Details
Charlie Kolar (TE)	Ques Sun	Forearm - 22 / 09 / 26	0-2	0-2	Details

San Francisco 49ers SF

No posts found.

L.A. Chargers Chargers LAC

No posts found.

San Francisco 49ers SF

49ers are 2-5 ATS in their last 7 games as a road underdog of 3.5-10.0.

Over is 6-2 in 49ers last 8 games as a favorite.

Over is 5-1 in 49ers last 6 games on fieldturf.

49ers are 2-7 ATS in their last 9 games as a road underdog.

49ers are 2-5 ATS in their last 7 games as an underdog of 0.5-3.0.

L.A. Chargers Chargers LAC

Under is 5-1 in Chargers last 6 games as a home underdog of 3.5-10.0.

Chargers are 4-1 ATS in their last 5 home games.

Over is 7-1 in Chargers last 8 Thursday games.

Chargers are 5-0-1 ATS in their last 6 games as a home favorite of 3.5-10.0.

Chargers are 4-0 ATS in their last 4 games as an underdog of 0.5-3.0.

Team	Win / Loss	ATS	OU
Minnesota Vikings MIN	3-0	3-0	1-2
San Francisco 49ers SF	3-0	2-1	2-1
Philadelphia Eagles PHI	2-1	0-3	1-2
Carolina Panthers CAR	1-2	1-2	1-2
Detroit Lions DET	2-1	1-2	3-0
Chicago Bears CHI	2-1	2-1	1-2
Seattle Seahawks SEA	2-1	1-2	1-2
N.Y. Giants Giants NYG	2-1	1-2	0-3
L.A. Rams Rams LAR	1-2	1-2	1-2
Dallas Cowboys DAL	1-2	1-1	2-1
Atlanta Falcons ATL	1-2	1-2	1-2
Washington Commanders WAS	1-2	2-1	2-1
New Orleans Saints NO	1-2	2-1	2-1
Green Bay Packers GB	1-2	0-2	2-1
Arizona Cardinals ARI	1-2	2-1	1-2
Tampa Bay Buccaneers TB	0-3	0-3	2-1

Team	Win / Loss	ATS	OU
Kansas City Chiefs KC	3-0	2-1	1-2
Buffalo Bills BUF	3-0	3-0	2-1
Jacksonville Jaguars JAC	2-1	2-1	1-2
Pittsburgh Steelers PIT	2-1	2-1	1-2
Las Vegas Raiders LV	3-0	3-0	1-2
Baltimore Ravens BAL	2-1	1-1	2-1
Denver Broncos DEN	2-1	2-1	1-2
Cincinnati Bengals CIN	2-1	2-1	2-1
Cleveland Browns CLE	2-1	2-1	2-1
N.Y. Jets Jets NYJ	1-2	1-1	1-2
New England Patriots NE	1-2	2-1	0-3
Indianapolis Colts IND	1-2	2-1	2-1
Miami Dolphins MIA	0-3	0-3	1-2
L.A. Chargers Chargers LAC	0-3	0-3	0-3
Houston Texans HOU	0-3	0-3	1-2
Tennessee Titans TEN	0-3	2-1	1-2

San Francisco 49ers

Pitchers

POS	Player

Hitters

POS	Player

Los Angeles Chargers

Pitchers

POS	Player

Hitters

POS	Player

Game Statistics

321

229

Total Yards

175

161

Passing Yards

146

Rushing Yards

Touchdowns

100

Field Goal %

Turnovers

Team	Last 5 Matches
San Francisco 49ers SF ( 3-0 )	W W W W W
L.A. Chargers Chargers LAC ( 0-3 )	L L L L W

10/04/26

4:25 pm ET

Denver Broncos DEN ( 2-1 )

San Francisco 49ers SF ( 3-0 )

vs
Matchup

10/04/26

4:25 pm ET

L.A. Chargers Chargers LAC ( 0-3 )

Seattle Seahawks SEA ( 2-1 )

vs
Matchup

George Kittle Tight End L.A. Chargers	3	Touchdowns	2	Omarion Hampton Running Back San Francisco
Omarion Hampton Running Back San Francisco	193	Rushing	166	Christian McCaffrey Running Back L.A. Chargers
Brock Purdy Quarterback L.A. Chargers	789	Passing	627	Justin Herbert Quarterback San Francisco
Christian McCaffrey Running Back L.A. Chargers	13	Receiving	12	Ladd McConkey Wide Receiver San Francisco
Khalil Mack Linebacker San Francisco	2	Sacks	2	Keion White Defensive End L.A. Chargers
Genesis Smith Safety San Francisco	2	Interceptions	1	Renardo Green Cornerback L.A. Chargers

team	w games_won	l games_lost	pf points
San Francisco 49ers SF	3	0	98
Seattle Seahawks SEA	2	1	75
L.A. Rams Rams LAR	1	2	61
Arizona Cardinals ARI	1	2	63
Carolina Panthers CAR	1	2	89
Atlanta Falcons ATL	1	2	51
New Orleans Saints NO	1	2	81
Tampa Bay Buccaneers TB	0	3	62
Philadelphia Eagles PHI	2	1	55
N.Y. Giants Giants NYG	2	1	46
Dallas Cowboys DAL	1	2	88
Washington Commanders WAS	1	2	75
Minnesota Vikings MIN	3	0	71
Detroit Lions DET	2	1	93
Chicago Bears CHI	2	1	89
Green Bay Packers GB	1	2	56

Game Preview

49ers vs. Chargers Point Spread: NFL Pre-Season Week 2 Odds, Prediction

The San Francisco 49ers travel to SoFi Stadium this Thursday night to take on the Los Angeles Chargers in both teams' second preseason contest.

Team	Win / Loss	ATS	OU
Minnesota Vikings MIN	3-0	3-0	1-2
San Francisco 49ers SF	3-0	2-1	2-1
Philadelphia Eagles PHI	2-1	0-3	1-2
Carolina Panthers CAR	1-2	1-2	1-2
Detroit Lions DET	2-1	1-2	3-0
Chicago Bears CHI	2-1	2-1	1-2
Seattle Seahawks SEA	2-1	1-2	1-2
N.Y. Giants Giants NYG	2-1	1-2	0-3
L.A. Rams Rams LAR	1-2	1-2	1-2
Dallas Cowboys DAL	1-2	1-1	2-1
Atlanta Falcons ATL	1-2	1-2	1-2
Washington Commanders WAS	1-2	2-1	2-1
New Orleans Saints NO	1-2	2-1	2-1
Green Bay Packers GB	1-2	0-2	2-1
Arizona Cardinals ARI	1-2	2-1	1-2
Tampa Bay Buccaneers TB	0-3	0-3	2-1

Team	Win / Loss	ATS	OU
Kansas City Chiefs KC	3-0	2-1	1-2
Buffalo Bills BUF	3-0	3-0	2-1
Jacksonville Jaguars JAC	2-1	2-1	1-2
Pittsburgh Steelers PIT	2-1	2-1	1-2
Las Vegas Raiders LV	3-0	3-0	1-2
Baltimore Ravens BAL	2-1	1-1	2-1
Denver Broncos DEN	2-1	2-1	1-2
Cincinnati Bengals CIN	2-1	2-1	2-1
Cleveland Browns CLE	2-1	2-1	2-1
N.Y. Jets Jets NYJ	1-2	1-1	1-2
New England Patriots NE	1-2	2-1	0-3
Indianapolis Colts IND	1-2	2-1	2-1
Miami Dolphins MIA	0-3	0-3	1-2
L.A. Chargers Chargers LAC	0-3	0-3	0-3
Houston Texans HOU	0-3	0-3	1-2
Tennessee Titans TEN	0-3	2-1	1-2

49ers vs. Chargers Prediction, Odds & Stats August 20, 2026

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Omarion Hampton

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