Colorado St. (12) vs. Memphis (5) Bracket Prediction: March Madness Odds

Sports Interaction Staff | Updated Mar 20, 2025

The 2025 NCAA Tournament features an intriguing first-round matchup between the No. 5 seed Memphis Tigers and the No. 12 seed Colorado State Rams.

AT
March 21, 2025, 2:00 PM ET
KeyArena
Memphis
26-5

This game is scheduled for Friday, March 21, at 2:00 p.m. ET at Ball Arena in Denver, Colorado. Both teams enter the tournament with momentum, setting the stage for a compelling contest.

Colorado St. vs. Memphis NCAA Tournament Point Spread and Betting

This 5 vs. 12 matchup is particularly intriguing, as No. 12 seeds have historically posed challenges for No. 5 seeds. Memphis’s success hinges on their ability to dictate a fast-paced game, leveraging their transition offense. Conversely, Colorado State aims to control the tempo, utilizing their efficient half-court sets. The availability of Memphis’s Tyrese Hunter is a critical factor; his presence would bolster the Tigers’ backcourt and transition game.

Assuming Tyrese Hunter is available, Memphis’s transition offense and PJ Haggerty’s scoring prowess provide them with a slight edge. However, Colorado State’s disciplined approach and current winning streak cannot be overlooked.

Colorado St. Rams

The Colorado State Rams, coached by Niko Medved, enter the tournament with a 25-9 record and are riding a 10-game winning streak, including a Mountain West Tournament championship. Nique Clifford is the team’s standout player, leading in multiple statistical categories with averages of 19.0 points, 9.7 rebounds, 4.4 assists, and 1.2 steals per game. The Rams excel in half-court offense, boasting a 46.1% field goal percentage in such situations, indicative of their methodical approach. 

Memphis Tigers

The Memphis Tigers, under coach Penny Hardaway, boast a 29-5 record and have secured the highest seed of Hardaway’s tenure. The team is led by dynamic guard PJ Haggerty, who averages 22.9 points per game. However, injuries to key players Tyrese Hunter (foot) and Dante Harris (ankle) pose challenges, with both listed as questionable for the game. Memphis thrives in transition, attempting 17.3% of its field goals in such situations, reflecting their up-tempo style. 

March Madness Prediction: Who Will Win Memphis vs. Colorado State?

SportsInteraction