Syracuse vs. Houston Bracket Prediction: March Madness Odds

Nik Kowalski | Updated Mar 24, 2021

Quentin Grimes scored a game-high 22 points on Sunday to go along with nine rebounds and two steals. Grimes has led Houston in scoring in both their tournament games, scoring 18 in their Round of 64 match.

March 27, 2021, 9:55 PM ET
Hinkle Fieldhouse
Pointspread +6.5 -110
Moneyline +200
Over / Under o +140.5


Betting Action


Pointspread -6.5 -110
Moneyline -241
Over / Under u +140.5


Betting Action


Buddy Boeheim’s got 55 points in two tournament games for a No. 11 Syracuse Orange club shooting 53.5 per cent from the field. It’s trouble for the No. 2 Houston Cougars that just survived a scare from the tenth-seeded Rutgers Scarlet Knights in the Round of 32. The Orange and Cougars will conclude Saturday’s Sweet Sixteen slate, facing off in a Midwest Region with the two, eight, 11, and 12 seeds remaining.

Tip-off at Hinkle Fieldhouse is scheduled for 9:55 p.m. EST.

Syracuse Orange vs. Houston Cougars NCAA Tournament Point Spread and Betting

Although it might be the Orange coming in with maximum confidence, it’s Houston entering on a nine-game winning streak and a 14-5 against the spread record over their last 19. Syracuse meanwhile has covered in six straight games and their last seven contests in March.

Oddsmakers have Houston as a 6-point favourite over Syracuse and the total set at 140. If this confirms anything it’s that Syracuse will go out guns blazing — 15 of their last 20 games as an underdog have gone over the total. Both teams have hit one over and one under this tournament.

Syracuse Orange

Jim Boeheim’s club is on a quite a run and his son Buddy is at the forefront. Boeheim’s 25 points against West Virginia led all scorers last Sunday. It also marked his fourth straight game in which he’s hit at least five three-pointers while shooting at least 50 per cent from the arc. He’s now made 29 triples in six games this month and is averaging 26 points per game.

Boeheim isn’t the only sharpshooter on the ‘Cuse, as sophomore guard Joseph Girard III also has seven made three-pointers in his last two games while averaging 12 points this tournament. The 2-3 zone has been working for the most part too, but West Virginia did score 72 on Syracuse in a three-point loss so a well-coached offence can still get theirs.

Houston Cougars

Without a gutsy effort from DeJon Jarreau last weekend, the Cougars might not be here. The senior guard left it all on the floor last Sunday, playing through a hip pointer that kept him out of most of Houston’s 87-56 tournament-opening win over Cleveland State. Jarreau went on to start against Rutgers in the Round of 32 and post 17 points and five rebounds on six-of-12 shooting.

Junior guard Quentin Grimes was the only other Cougar starter with at least four points against Rutgers, scoring a game-high 22 to go with nine rebounds and two steals. Grimes has led Houston in scoring in both their tournament games, scoring 18 in their Round of 64 match.

March Madness Score Prediction: Who Will Win Orange vs. Cougars?