New Mexico (10) vs. Michigan St. (2) Bracket Prediction: March Madness Odds

Sports Interaction Staff | Updated Mar 23, 2025

The stakes are rising and so is the pressure as No. 2 seed Michigan State meets No. 10 seed New Mexico in a second-round clash that pits tradition against tenacity.

New Mexico
25-6
AT
March 23, 2025, 8:40 PM ET
Rocket Mortgage FieldHouse

Set for Sunday, March 23 at Rocket Arena in Cleveland, this matchup features a battle-tested Spartans squad coached by March maestro Tom Izzo, going up against a surging Lobos team that just knocked off a powerhouse and isn’t ready to go home yet.

New Mexico vs. Michigan St. NCAA Tournament Point Spread and Betting

Michigan State is favored by 7.5 points over New Mexico, with the total set at 148.5 points. The Spartans’ moneyline is -325, while the Lobos offer a +260 return for those considering an upset.

This game presents a fascinating contrast in styles: Michigan State’s disciplined, half-court offense against New Mexico’s fast-paced, transition-heavy approach. The Spartans will look to control the tempo, utilizing their size advantage to dominate the boards and limit New Mexico’s fast-break opportunities.

Conversely, the Lobos will aim to speed up the game, relying on Dent’s playmaking abilities to create open looks. The battle between Walker and Dent will be pivotal, as both guards are instrumental in setting the tone for their respective teams. Additionally, Michigan State’s perimeter defense will be tested against New Mexico’s three-point shooting, a factor that could sway the game’s outcome.

Best Bets:

  • Michigan State -7.5: Given their defensive strengths and ability to control the game’s tempo, the Spartans are likely to cover the spread. 
  • Under 147.5 total points: Michigan State’s defensive approach may limit New Mexico’s scoring opportunities, making the under a viable option.

New Mexico Lobos

The New Mexico Lobos have been one of the tournament’s feel-good stories, entering this matchup with a 27-7 record. Under Richard Pitino’s guidance, the Lobos have embraced an up-tempo style, averaging 78.5 points per game. Sophomore guard Donovan Dent has been sensational, averaging nearly 21 points and over six assists per game. In their first-round upset over Marquette, Dent delivered a stellar performance, contributing 21 points and six assists. The Lobos’ ability to push the pace and their defensive resilience have been key factors in their tournament run.

Michigan State Spartans

The Michigan State Spartans have been a model of consistency this season, boasting a 28-6 record under the leadership of Tom Izzo. Their balanced attack features multiple scoring options, with senior guard Tyson Walker leading the charge. Walker’s ability to penetrate defenses and his prowess from beyond the arc make him a focal point of the Spartans’ offense. In their first-round victory over Bryant, Michigan State showcased their depth, with four players scoring in double figures. Their defensive tenacity and rebounding strength have been cornerstones of their success, making them a formidable opponent for any team.

NCAA Prediction: Who Will Win New Mexico vs. Michigan State?

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