Cleveland Cavaliers vs. Boston Celtics Prediction, NBA Odds

Payton Matthews | Updated Feb 27, 2025

NBA: Memphis Grizzlies at Cleveland Cavaliers

It’s a potential Eastern Conference Finals preview that highlights Friday’s NBA schedule as the Cleveland Cavaliers visit the Boston Celtics.

Cleveland
64-18
AT
February 28, 2025, 7:30 PM ET
TD Garden
Boston
61-21
Pointspread +1.5 -115
Moneyline -102
Over / Under o +232.5
Pointspread -1.5 -105
Moneyline -118
Over / Under u +232.5

Boston opened as 3-point favourites to win, with a total of 232 on the NBA odds.

Cavaliers vs. Celtics NBA Betting Odds

Much more often than not, either the top seed in the Eastern or Western Conference wins the NBA Finals each year, and it has happened each of the past two seasons with Boston in 2024 and Denver in 2023. If the Celtics are going to repeat as NBA champions – and they are +210 to do so – it almost surely will be as the second-place team in the East as they are 6.5 games behind first-place Cleveland.

It’s not a sure thing that the NBA-best Cavaliers will lose seven more games, so even a Celtics win tonight to close the gap a bit might not matter in the long run. To win the East, Boston is -125 and Cleveland +230. They would only meet in the East Finals after Friday as it marks the final regular-season meeting. The Cavs lead 2-1 but lost their lone trip to Beantown, 120-117, in mid-November.

All-Star Donovan Mitchell has torched the Celtics this season in averaging 33.7 points per game. Jarrett Allen averages 11.7 points and 13.0 rebounds. All-Star Jayson Tatum leads Boston in the series averaging 29.3 points and 8.0 rebounds.

The Celtics beat the Cavs in five games in the 2024 East semifinals, but the teams have split the past 10 regular-season matchups with the over-under at 6-4.

Cleveland Cavaliers

Cleveland is on an NBA-high eight-game winning streak following a thoroughly impressive 40-point win in Orlando on Tuesday in a 2024 playoff rematch. It tied as the Cavs’ largest road win ever and was such a rout that star Donovan Mitchell played only 23 minutes. Mitchell’s 197 made 3-pointers are sixth-most in the league, and he is on the verge of becoming the first player in Cavs history to have multiple seasons with at least 200 made. Evan Mobley had 17 points, eight rebounds and two blocks Tuesday and is the new betting favourite for NBA Defensive Player of the Year with San Antonio’s Victor Wembanyama, the former favourite, now out for the season. Mobley ranks fifth in the NBA in contested shots per game (10.2), third in in net rating (15.3) and second in overall plus-minus (+503). All-Star point guard Darius Garland has missed the past two with a left thigh contusion but will play. The Cavs have made at least 10 3-pointers in a team-record 63 straight games, which is the third-longest streak of double-digit makes in league history. The over is 5-2 in Cleveland’s past seven games.

Boston Celtics

Boston had a six-game winning streak snapped Wednesday in a 117-97 loss in Detroit, but you could almost see that coming as the Celtics were in the second of a back-to-back and without All-Star Jaylen Brown, who should play Friday. Boston is on pace to set numerous franchise and NBA records for 3-pointers and made 11 of them on 16 attempts in the second quarter Wednesday. That’s one shy of the NBA mark shared by Boston from when it hit 12 3-pointers in the second quarter against the Clippers on Nov. 25. Of the 35 points scored in that second quarter in Detroit, 33 were from deep — a rate of 94.3 per cent. It marked the first time in league annals that a team scored more than 90 per cent of its points in a quarter from 3-point range (minimum 30 points scored). It was only the fifth time this season Boston was held under 100 points. This starts a season-long seven-game homestand. The Celtics are 5-2 ATS in their past seven overall.

NBA Prediction: Who Will Win Cavaliers vs. Celtics?

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