St. Louis Cardinals vs. Toronto Blue Jays: Odds, Prediction

Payton Matthews | Updated Jul 26, 2022

The Toronto Blue Jays are looking for a seventh straight win as they prepare to host the St. Louis Cardinals for the first of a short two-game interleague series on Tuesday.

St. Louis
July 26, 2022, 7:07 PM ET
Rogers Centre
Runline +1.5 +101
Moneyline +194
Over / Under o +9


Betting Action


Runline -1.5 -121
Moneyline -234
Over / Under u +9


Betting Action


Streaking Toronto opens a six-game homestand Tuesday by welcoming future Hall of Famer Albert Pujols and the St. Louis Cardinals to town. The Jays are -230 favourites for the opener on the MLB odds.

Betting Analysis

This will be the last chance for Toronto-area fans to see Pujols in person as he’s retiring after the season. The 42-year-old was named an All-Star this year but that was an “honorary” legend pick as Pujols isn’t hitting much. He will go down as one of the greatest hitters ever, however, and is a lock first-ballot Hall of Famer. St. Louis has another future Hall of Famer in catcher Yadier Molina, but he hasn’t played since early June due to knee problems and won’t be back for this series.

If the Jays and Cardinals play again after Wednesday this year, it will be in the World Series. Not out of the question as both should be playoff teams. Toronto is a heavy favourite to earn a Wild-Card spot and St. Louis should either win the NL Central or earn its own Wild-Card spot. The Cards also have been rumoured as a potential landing spot for Nationals superstar outfielder Juan Soto, who is being shopped.

Toronto split two games in St. Louis from May 23-24. Danny Jansen had a nice series with two homers and four RBIs. George Springer was 2-for-7 with a triple, homer, three RBIs and three runs scored. Paul Goldschmidt was 3-for-8 in the series with a homer and four RBIs – he hit a walk-off grand slam in the bottom of the 10th inning in the Cards’ 7-3 win in the opener.

The Cardinals have blanked the Blue Jays in four of their 20 all-time games played at Rogers Centre. The Cards played there in 2014 and that series featured the last triple play turned by St. Louis.

St. Louis Cardinals

Massively big news as the Cardinals’ two best hitters, All-Stars Nolan Arenado and Goldschmidt (he might win NL MVP), didn’t make the trip because they are unvaccinated for COVID. Goldschmidt is batting .335 with 24 homers and 77 RBIs, while Arenado is batting .296 with 18 homers and 59 RBIs. Backup catcher Austin Romine is also out.

It’s 23-year-old right-hander Andre Pallante (3-4, 3.34 ERA) on the mound. He hasn’t been quite as sharp this month with an 8.16 ERA in three outings. He pitched one third of an inning in relief vs. Toronto on May 23. Pallante 0-1 with a 2.57 ERA and five strikeouts in three games (one start) vs. interleague opponents. St. Louis is 2-6 in its past eight road games.

Toronto Blue Jays

Toronto’s first series out of the break couldn’t have gone much better as the Blue Jays swept three in Boston, taking each by at least three runs. They lead the majors with a .267 average overall. Vladimir Guerrero Jr. was 4-for-5 on Sunday, his fourth multi-hit performance in his last six games, raising his batting average from .268 to .280 during that span.

It’s right-hander Jose Berrios (7-4, 5.22 ERA) on the mound. He has been solid this month at 2-0 with a 3.09 ERA in four starts. Berrios took a no-decision vs. the Cards on May 23, allowing three earned over 6.1 innings. Corey Dickerson is 5-for-11 with three doubles and a homer off Berrios in his career. Dickerson doesn’t play every day but with the Cardinals short-handed and those splits, he’ll likely be in there Tuesday. The Jays have won seven straight following an off day.

MLB Prediction: Who Will Win Cardinals vs. Blue Jays?