NFL Spreads Week 11: Best Picks Against the Spread

Ricky Rothstein | Updated Nov 14, 2016

NFL: Carolina Panthers at New Orleans Saints

If you had predicted that the Dallas Cowboys would have the NFL’s best record through 10 weeks of the 2016 regular season while starting both a rookie quarterback and running back in every game, well, you are much wiser than me. But thanks to New England’s upset loss to Seattle on Sunday, the Cowboys are the only one-loss team in the league. Here’s a quick look at all Week 11 matchups with Sports Interaction NFL odds. Games on Sunday unless noted. The Falcons, Broncos, Jets and Chargers are on the bye.

New Orleans Saints at Carolina Panthers, Thursday

Point spread: Carolina -4 Total: 51.5 I will have a preview of this NFC South matchup on Tuesday at Sports Interaction. New Orleans goes for the season sweep after a 41-38 home victory in Week 6 thanks to a monster day from Drew Brees. Pick ATS: Panthers

Pittsburgh Steelers at Cleveland Browns

Point spread: Pittsburgh -9.5 Total: 49.5 Ah, the Browns. They are off to the first 0-10 start in franchise history and have a single win in their past 21 games. You know who the starting quarterback was in that victory? Johnny Manziel. Wow. Pittsburgh QB Ben Roethlisberger almost never loses to Cleveland as the Ohio native still holds a grudge that the team he grew up rooting for passed on him in the first round of the 2004 draft. The Browns took tight end Kellen Winslow II instead. Oops! Pick ATS: Steelers

Baltimore Ravens at Dallas Cowboys

Point spread: Dallas -7.5 Total: 45 The Ravens are in sole possession of first place in the AFC North after their easy win over Cleveland last Thursday and Pittsburgh’s home loss to Dallas on Sunday. The Cowboys won that thriller 35-30 on an Ezekiel Elliott 32-yard TD run with just nine seconds to go. The rookie had another huge game and might be your NFL MVP favourite right now. Then again, rookie QB Dak Prescott also is in that mix. Pick ATS: Ravens

Jacksonville Jaguars at Detroit Lions

Point spread: Detroit -6.5 Total: 47 The Lions come off their bye week but that really worked out well for them as every other NFC North team lost on Sunday and now Detroit finds itself tied for first. Jacksonville is basically a dead team walking on a four-game losing streak and there’s no doubt these are the final weeks of Gus Bradley’s head coaching career in Jacksonville. Pick ATS: Lions

Tennessee Titans at Indianapolis Colts

Point spread: Indianapolis -3 Total: 52 The Colts, off their bye week, have owned the Titans over the years. Indy won in Nashville 34-26 in Week 7. Andrew Luck threw a 7-yard touchdown pass to Jack Doyle with 1:55 left to put Indianapolis ahead to stay. Luck had 353 yards passing and three scores in the Colts’ 10th straight win in the series. The Titans took possession of the ball down 27-23 with under two minutes left, but QB Marcus Mariota was strip-sacked and it was returned for a 14-yard TD by Robert Mathis to clinch it. Mariota had a big game on Sunday in Tennessee’s upset of Green Bay. Pick ATS: Colts

Buffalo Bills at Cincinnati Bengals

Point spread: TBA Total: TBA Short week for Cincinnati as it played Monday night at the New York Giants. The Bills are off their bye week. The Bengals won in Buffalo in Week 6 last season, 34-21. Cincinnati blew open a close game by scoring 17 points on their first three drives of the second half. Andy Dalton threw three TD passes. Bills starting QB Tyrod Taylor was out injured. Pick ATS: Bengals

Tampa Bay Buccaneers at Kansas City Chiefs

Point spread: Chiefs -9 Total: 44.5 Tampa comes off its first home win of the season, a 36-10 blowout of Chicago. Jameis Winston threw for 312 yards and two scores and the Bucs’ defense forced four turnovers. Tampa already has impressive road wins this year in Atlanta and Carolina. The Chiefs moved into a tie for first in the AFC West by rallying from a 17-0 deficit to beat the Panthers on Sunday thanks to forcing a Carolina turnover in the final seconds. It was Kansas City’s fifth straight win. Pick ATS: Bucs

Chicago Bears at New York Giants

Point spread: TBA Total: TBA The Giants are on a short week as they hosted Cincinnati on Monday. Chicago was routed at Tampa Bay as Jay Cutler kept turning the ball over. Rookie running back Jordan Howard was the lone bright spot with 100 yards rushing on 15 carries. The Bears and Giants haven’t met since 2013, a 27-21 Chicago home win. Eli Manning was picked off three times. Pick ATS: Giants

Arizona Cardinals at Minnesota Vikings

Point spread: Pick’em Total: 41 Two playoff teams from last year, and they would have met in the divisional round had Vikings kicker Blair Walsh not hooked a 27-yard potential winning field goal in the final seconds of Minnesota’s home wild-card round loss to Seattle. The Vikings did visit the Cardinals in Week 14 in 2015 and lost 23-20. Memorable ending as Minnesota was in field-goal range in the final seconds, but Vikings QB Teddy Bridgewater allowed himself to be sacked instead of throwing the ball away, and time ran out. Pick ATS: Cardinals

Miami Dolphins at Los Angeles Rams

Point spread: Pick’em Total: 40.5 Second straight game in southern California for the Dolphins as they won in San Diego on Sunday, 31-24. Linebacker Kiko Alonso scored the winning touchdown on a 60-yard interception return with about a minute left. It was Miami’s fourth victory in a row. The Dolphins are staying in California this week to practice. You rarely win in the NFL when not scoring a TD, but the Rams did that for the second time in 2016 on Sunday, 9-6 at the Jets. There has been some talk that rookie No. 1 overall pick Jared Goff might finally make his Rams debut in this one so monitor that. Pick ATS: Dolphins

New England Patriots at San Francisco 49ers

Point spread: New England -14 Total: TBA This looks like the biggest mismatch of the season. And it will matter to Patriots quarterback Tom Brady as he grew up not far from San Francisco in San Mateo and was a huge 49ers fan. But he has never started a regular-season game there. The Patriots last visited in 2008 and Brady was out for the season due to a knee injury. New England looks to avoid a second loss in a row after being surprised at home Sunday night be Seattle. San Francisco played Arizona tough Sunday but still lost its eighth consecutive game. Pick ATS: 49ers

Philadelphia Eagles at Seattle Seahawks

Point spread: Seattle -4.5 Total: 45.5 This could be a major trap game for Seattle off that huge win in New England on Sunday night in a terrific rematch of the Super Bowl from two seasons ago. While the Seahawks lost that Super Bowl because of a goal-line stand by the Pats, Seattle won Sunday’s game with its own goal-line stand. Philadelphia beat visiting Atlanta 24-15 on Sunday to remain unbeaten at home. The Eagles are just 1-4 away from home, however. Pick ATS: Seahawks

Green Bay Packers at Washington Redskins

Point spread: Washington -2.5 Total: 50 This is the Sunday night game, and I will have a preview of it later this week here at Sports Interaction. It’s a rematch from last year’s wild-card round of the playoffs, a 35-18 Green Bay road win. Pick ATS: Redskins

Houston Texans at Oakland Raiders, Monday

Point spread: Oakland -5 Total: 46 Look for a preview of the Monday night game later this week. The AFC West co-leading Raiders come off their bye and they are the “home” team for this matchup in Mexico City. It’s the NFL’s first game there since 2005 and first-ever Monday night game outside the United States. Pick ATS: Raiders