NFL Point Spreads Week 6: Best Picks Against the Spread

Ricky Rothstein | Updated Nov 06, 2017

steelers vs chiefs week 6

It was a rough Sunday around the NFL as two of the league’s best players and biggest names, the Giants’ Odell Beckham Jr. and Texans’ J.J. Watt, suffered likely season-ending injuries. For this week, on the bye are Buffalo, Cincinnati, Dallas and Seattle. Here’s a quick look at all the Week 6 matchups with Sports Interaction NFL odds. Games Sunday unless noted.

Philadelphia Eagles at Carolina Panthers, Thursday

Potential playoff preview as both are 4-1, with Philadelphia leading the NFC East and Carolina atop the NFC South. Both had impressive wins Sunday. The Eagles trashed the visiting Cardinals 34-7 behind 304 yards and four TD passes from Carson Wentz. The Panthers won in Detroit, 27-24, as Cam Newton threw for 355 yards and three touchdowns. Carolina trailed 10-3 in the second before scoring 24 straight points.

Point spread: Panthers -3 Pick ATS: Carolina

Miami Dolphins at Atlanta Falcons

Atlanta comes off its bye. It was beaten for the first time this season in Week 4, upset 24-17 at home by Buffalo. The Falcons led the league in scoring last year at 33.9 points per game but are down to 26.0 in 2017. Miami finally had its home opener on Sunday and beat Tennessee 16-10 despite just 178 yards of offense. Fans were booing struggling QB Jay Cutler nearly the entire game and calling for backup Matt Moore, but Coach Adam Gase is sticking with Cutler for now.

Point spread: Falcons -10.5 Pick ATS: Miami

Green Bay Packers at Minnesota Vikings

It’s a short week for Minnesota as it was in Chicago on Monday, beginning life without top running back Dalvin Cook as he suffered a season-ending injury in Week 4. It was likely that the Vikings were going to get back QB Sam Bradford vs. the Bears. He hadn’t played since Week 1 due to a knee injury. Green Bay rallied from a 15-point deficit and won in Dallas, 35-31, on an Aaron Rodgers TD pass in the final seconds. These NFC North rivals split in 2016, each winning at home.

Point spread: TBA Pick ATS: TBA

Detroit Lions at New Orleans Saints

New Orleans was off in Week 5. Detroit was upset at home by Carolina, 27-24. Matthew Stafford threw two fourth-quarter passes to get the Lions within three points but couldn’t get the ball back after his second score with 3:22 to go. These teams met each of the past three seasons and Detroit won them all – the previous two in the Big Easy.

Point spread: Saints -4 Pick ATS: Detroit

New England Patriots at New York Jets

Yeah, because everyone expected the Patriots and Jets to have matching 3-2 records entering Week 6. Many didn’t believe the Jets would win three games all season, much less in a row. They won in Cleveland on Sunday, 17-14. The Pats are on extra rest after winning 19-14 in Tampa Bay last Thursday as the New England defense played easily his best game of the season. It was the 186th regular-season victory for Tom Brady, tying Brett Favre and Peyton Manning for the most by a QB. The Patriots swept the Jets last year and have taken five of the past six meetings – all decided by a touchdown or less but one.

Point spread: Patriots -9.5 Pick ATS: New England

San Francisco 49ers at Washington Redskins

There’s one clear storyline here: Kirk Cousins. The Redskins quarterback is expected to hit free agency after this season, and it’s well known around the league that he is very interested in playing for the 49ers. Why? Their new head coach is Kyle Shanahan, Cousins’ one-time offensive coordinator in Washington.  The two still have a great relationship. The Redskins come off their bye week, while the 49ers are one of three winless teams.

Point spread: Redskins -10 Pick ATS: San Francisco

Chicago Bears at Baltimore Ravens

Short week for Chicago as it hosted Minnesota on Monday night in the first NFL start for rookie No. 2 overall pick quarterback Mitchell Trubisky. Baltimore ended a two-game slide with a 30-17 win in Oakland. Potentially bad news here for Trubisky and the Bears: Under coach John Harbaugh, the Ravens are 10-0 at home against rookie QBs.

Point spread: TBA Pick ATS: TBA

Cleveland Browns at Houston Texans

Houston lost Watt, a three-time NFL Defensive Player of the Year, to a broken leg in Sunday’s night’s home loss to Kansas City. It’s possible he might return late in the season. At this year’s draft, the Browns traded the No. 12 overall pick to Houston for the Texans’ No. 25 overall selection in 2017 and their first-round pick next year. Advantage Houston so far, as it took Clemson quarterback Deshaun Watson and he’s an NFL Offensive Rookie of the Year favourite. Meanwhile, the Browns continue to have quarterback questions as they have since 1999. Cleveland pulled struggling rookie QB DeShone Kizer from Sunday’s home loss to the Jets. Coach Hue Jackson hasn’t named his starter yet for this week. The Browns are 1-20 under Jackson.

Point spread: Texans -10.5 Pick ATS: Cleveland

Tampa Bay Buccaneers at Arizona Cardinals

Tampa lost 19-14 at home to New England last Thursday as kicker Nick Folk missed three field goals and an extra point. The team is bringing in some kickers Monday for a tryout and then will decide whether or not to replace Folk. Arizona was routed 34-7 in Philadelphia on Sunday. The Cards simply can’t run the ball without the injured David Johnson and managed only 31 yards on the ground vs. Philly.

Point spread: Bucs -2 Pick ATS: Tampa Bay

Los Angeles Rams at Jacksonville Jaguars

The Rams entered Sunday’s home game vs. Seattle leading the NFL in scoring but lost 16-10. Jared Goff looked more like his rookie version in completing just 22 of 47 and being picked off twice. Jacksonville pulled off the biggest upset of Week 5, 30-9 in Pittsburgh. The Jags picked off Ben Roethlisberger five times, returning two for touchdowns.

Point spread: Jaguars -2.5 Pick ATS: Jacksonville

Pittsburgh Steelers at Kansas City Chiefs

Potential playoff preview between division leaders and a rematch of last season’s AFC Divisional Round game in Kansas City. The Steelers won that 18-16 despite not scoring a touchdown. Chris Boswell set an NFL playoff record with six field goals.  The Chiefs were held to 166 yards, but this year’s offense is vastly superior to the 2016 version. Kansas City remains the NFL’s only unbeaten team.

Point spread: Chiefs -3 Pick ATS: Kansas City

Los Angeles Chargers at Oakland Raiders

The Chargers got their first victory Sunday, beating the winless Giants 27-22 to end a nine-game losing streak dating to last season. Melvin Gordon rushed for 105 yards and caught two TD passes. The Bolts had been 4-12 dating back to the start of last season in games decided by eight points or fewer. The Raiders played without injured QB Derek Carr (back) and predictably struggled behind backup E.J. Manuel in a 30-17 home loss to Baltimore. It’s possible Carr returns this week. The Raiders swept the Chargers in 2016, winning each by a field goal.

Point spread: TBA (for Carr) Pick ATS: TBA

New York Giants at Denver Broncos

Sunday night game. Probably no team had a worse Week 5 than the Giants as they dropped to 0-5 and saw their top three receivers, Odell Beckham Jr., Sterling Shepard and Brandon Marshall, leave with ankle injuries. Beckham’s season is likely over as he fractured his. Denver comes off its bye.

Point spread: Broncos -10.5 Pick ATS: NY Giants

Indianapolis Colts at Tennessee Titans, Monday

The Colts have won 11 straight against the Titans, but they had QB Andrew Luck for many of those games. He has yet to play this season off shoulder surgery. Luck finally returned to practice last week but he won’t be going here. The Titans lost Sunday in Miami without starting QB Marcus Mariota due to a hamstring injury. His status will determine this line.

Point spread: TBA Pick ATS: TBA