How to Bet Week 8 of the 2025 NFL Season: Will the surging Chiefs continue to climb the standings?

For the first time in a while, Week 8 will see no international games and only one Monday Nighter.

We’re back with picks and predictions for all the Week 8 prime-time games and couple Sunday afternoon matinees.

Here’s everything you need to know to bet Week 8 of the 2025 NFL season.

Sports Interaction

Pick
Odds
Over +44.5
Over/Under
NFL • Minnesota Vikings @ Los Angeles Chargers
-115 on Sports Interaction
CLOSED • 10/24/2025
Tally (Win %)
4-3-0 (57%)
Money Meter
$6.29
ROI
9.0%
Betslip #1761157965029-53c6-483

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TNF Vikings at Chargers

Thursday Night Football opens with a rare meeting between the Vikings and Chargers, who are each coming off a loss.

The Los Angeles defence has fallen off a cliff lately. Over the last three weeks, the Chargers have allowed the most yards per play in the NFL while giving up at least 27 points each to the Commanders, Dolphins and Colts.

Looking at Minnesota, Vikings fans might be nervous with Carson Wentz starting for the injured J.J. Mccarthy, but Wentz has actually been solid, passing for over 300 yards in two of his last three starts.

Both teams have been playing high scoring football lately and I like that to continue in Week 8.

Pick: Over 44.5

49ers at Texans

San Francisco and Houston have been two of the more surprising teams this season, but for different reasons. The 49ers are in a three-way tie for top spot in the NFC West with a 5-2 record despite injuries throughout the lineup, while the Texans are a disappointing 2-4.

Early money, however, came in heavily on Houston. The Texans opened as 1.5-point underdogs, but as of Wednesday afternoon, the line is now Houston -1.5.

That line movement is likely due to the status of 49ers quarterback Brock Purdy, who was expected to return from injury this week. Reportedly, Purdy is progressing slower than expected so Mac Jones might get the start again after throwing for just 152 yards with no TDs and one interception last week.

The Texans are going to lean heavily on their elite defensive unit in this one. Houston has the fourth-ranked total defence in the NFL and they’re particularly effective against the pass, holding opposing teams to 179 passing yards per game.

I don’t like the way this line keeps flip flopping, so I’m going to stick to the total and count on a lower scoring game with a backup quarterback in San Francisco facing an elite defence in Houston.

Pick: Under 41.5

Cowboys at Broncos

The Denver Broncos are rolling with a four-game win streak and lead the AFC West with a 5-2 record. Next up for the Broncos, is a home date with the 3-3-1 Dallas Cowboys.

Denver has some making up to do with bettors after last week’s wild 33-32 win against the Giants. The Broncos were favourites by a touchdown, but actually trailed 19-0 after three quarters. Denver used a 33-point fourth quarter to win outright by one point, but miss covering by six.

Dallas should feel good after pumping the Commanders by 22 points last week, but keep in mind, Washington has a weak secondary and Jayden Daniels left the game early with an injury.

I lean Broncos in this spot. Despite last week’s debacle, Denver’s defence is still ranked sixth against the pass and they’ll be the toughest unit the Cowboys have faced in a while. This will be a defensive smothering by the Broncos.

Pick: Broncos -3.5, Under 50.5

SNF Packers at Steelers

Two storied franchises and division leaders meet for Sunday Night Football, with 4-2 Pittsburgh hosting 4-1-1 Green Bay.

One of the more perplexing stories of the season has been the Steelers putrid defence. The once great unit ranks 31st against the pass, 17th against the run and 28th overall. Even a weak Bengals rushing attack was able to gain 142 yards against Pittsburgh last week.

That doesn’t bode well against a Packers offence that has one of the most run-heavy playbooks. Green Bay runs the ball at the third-highest rate in the NFL and they are No. 5 in success rate per run.

I like the Packers to slow this game down and win on the run. That should lead to a comfortable victory in a low scoring contest.

Pick: Packers -3, Under 45.5

MNF Commanders at Chiefs

Week 8 concludes at Arrowhead, as the surging Kansas City Chiefs look to build on their 4-3 record when they host the 3-4 Washington Commanders.

This line has exploded and that scares me a little. Kansas City opened as 9.5-point favourites, but early betting action has pushed the line to Chiefs -12.5 as of Wednesday afternoon.

A big part of that line shift is the hamstring injury that is keeping Commanders quarterback Jayden Daniels out. Backup journeyman Marcus Mariota will start against KC after completing only four of 10 passes in relief of Daniels last week, finishing with 63 yards, no TDs and an interception.

Meanwhile, Chiefs quarterback Patrick Mahomes is starting to torch teams with Rashee Rice back from suspension and Xavier Worthy healthy. Kansas City’s offence is humming, with the team averaging 31.5 points over their last four games.

The spread terrifies me in this game, so I’m going to coward out and avoid it altogether. One thing I am confident about, however, is Mahomes and co. will terrorize Washington’s defence.

Pick: Over 47

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