Buccaneers vs. Cowboys Point Spread: NFL Week 1 Odds, Prediction

Payton Matthews | Updated Sep 05, 2022

Tom Brady starts his 23rd NFL season on the road in Dallas as the Buccaneers prepare to face the Cowboys.

Tampa Bay
September 11, 2022, 8:20 PM ET
AT&T Stadium
Pointspread -2.5 -110
Moneyline -141
Over / Under o +49.5


Betting Action


Pointspread +2.5 -110
Moneyline +117
Over / Under u +49.5


Betting Action


The first Sunday night game of the 2022 NFL season is a marquee matchup indeed and a rematch of a Week 1 opener last year as the Tampa Bay Buccaneers visit the Dallas Cowboys. Tom Brady and the Bucs are short favourites to win on the NFL odds.

NFL Point Spread and Betting Analysis

Will this be the final season opener for Bucs quarterback Tom Brady? He retired this offseason for a while – and reportedly almost tried to join the Miami Dolphins – before changing his mind. I’m not going to get into a bunch of gossip but there are rumours his wife, supermodel Gisele Bündchen, is very unhappy that TB12 returned to football and that was why Brady left training camp for 11 days.

This could easily be a playoff preview as the Bucs are pretty heavy favourites to win the NFC South again and the Cowboys are favoured (albeit not by much, over the Eagles) to capture the NFC East for a second straight season.

As noted above, these teams met last year in Week 1 and it was the Kickoff Game in Tampa. Spectacular game as the Bucs rallied for a 31-29 victory on a Ryan Succop 36-yard field goal with two seconds left. Brady threw for 379 yards and four scores but two picks. Dak Prescott threw for 403 yards and three scores.

Tampa Bay Buccaneers

Tampa Bay’s offensive line was hammered by injuries in camp/preseason, and Pro Bowl centre Ryan Jensen is on injured reserve so he’s not playing in the opener. He had been replaced in the starting lineup this summer by second-year man Robert Hainsey, but Hainsey is banged up too – although it’s trending as if he will play. Likely starting guard Aaron Stinnie is done for the season with a torn left ACL and MCL. He was the leading candidate to replace 2021 starter Ali Marpet, who surprisingly retired. Tampa projects to have three new starters in the interior, two of whom will be making their first starts in their NFL careers.

Pro Bowl receiver Chris Godwin is working his way back from a torn ACL suffered last season and is iffy for Week 1. Free-agent addition WR Russell Gage got hurt this summer but likely will be ready. The Bucs also got Brady a future Hall of Famer at receiver in signing Julio Jones. Rather amazingly, Brady’s teams are 1-12 ATS in their past 13 prime-time games (kickoff of 7 ET or later) dating to his New England days. This will be the Bucs head coaching debut of Todd Bowles.

Dallas Cowboys

Few coaches enter the season on a hotter seat than the Cowboys’ Mike McCarthy as most of the NFL world assumes Jerry Jones will fire McCarthy and hire former Saints coach and Dallas assistant Sean Payton after the season if the Cowboys disappoint. Yes, Dallas won the NFC East last year – and had an NFL-best 13-4 against the spread read – but was upset at home by San Francisco in the Wild-Card round of the playoffs. The Cowboys will be without eight-time Pro Bowl left tackle Tyron Smith until likely December due to a serious hamstring injury that required surgery. For his career, the Cowboys are 17-16 without Smith.

Receivers Michael Gallup and James Washington are both out – meaning the Bucs surely will double-team CeeDee Lamb. Rookie Jalen Tolbert will be thrust into a big role immediately. Dallas may try to run more with its 1-2 punch of Ezekiel Elliott (perhaps his final season in Big D) and Tony Pollard. The Cowboys have covered seven straight games as home dogs.

NFL Prediction: Who Will Win Buccaneers vs. Cowboys?