Bills vs. Giants Point Spread: NFL Predictions, Week 2 Odds

Charlie Grant | Updated Sep 10, 2019

saquon barkley

The Buffalo Bills are road favourites for the first time since the 2017 campaign as they travel to the Meadowlands to take on Saquon Barkley and the New York Giants.

September 15, 2019, 1:00 PM ET
MetLife Stadium
Pointspread -1 -112
Moneyline -122
Over / Under o +44.5


Betting Action


Pointspread +1 -108
Moneyline +101
Over / Under u +44.5


Betting Action


The Bills are seeking a second straight win at MetLife Stadium after a stunning, come-from-behind victory against the New York Jets last weekend.

NFL Point Spread and Betting Analysis

The G-Men opened as 2.5-point home dogs at Sports Interaction. The point spread dropped half a point to +2 by midweek. The game total opened at 42.5 and quickly moved up a point to 43.5. The action is near split on the spread with 51 percent of the bets on the Bills. The handle isn’t as even on the Over/Under line. About 65 percent of Sports Interaction customers expect this game to go Over 43.5 points.

Buffalo Bills at NY Giants

  • Buffalo Bills -114 -1
  • NY Giants -106 +1

Buffalo has long been one of the cellar dwellers in the AFC, but the club has a knack for following up strong performances. The Bills are 4-1 against the spread in their last five games coming off an outright win.

The Giants are 1-6-1 ATS in their last eight home contests and 2-8 against the number in their last 10 September games.

The Bills defence held the Jets in check last weekend. Low-scoring games have been commonplace for games involving Buffalo. The Under is 7-1 in the Bills’ last eight away dates.

Buffalo Bills

The final score might not show it, but the Bills completely dominated the Jets in Week 1. Buffalo came from down 16 to win outright 17-16, but the club outgained Gang Green 358 to 203 in yards.

Eli Manning and his creaky, 38-year-old frame could be in trouble against the Bills’ pass rush. Buffalo sacked Sam Darnold four times in Week 1.

Josh Allen doesn’t mind defensive pressure. The second year QB rushed for 38 yards and a touchdown against the Jets. He gained over 600 yards on the ground last season and he already has nine career rushing touchdowns.

New York Giants

Expect to see second year running back Saquon Barkley feature early and often for the Giants. New York will likely be without wide receiver Sterling Shepard. The fourth year playmaker out of Oklahoma is in the concussion protocol after suffering a blow to the head in last weekend’s loss to the Giants. Shepard and Golden Tate were expected to be the top two wide receiver targets for Eli Manning this season. Tate is out for the first four games due to suspension.

Who Will Win Bills vs. Giants?