2025 NFL Betting Odds and Predictions: Passing yards and TDs leader, most receptions

With the Dallas Cowboys and Philadelphia Eagles set for an NFC East showdown on Thursday Night Football kickoff on September 4, the 2025 NFL regular season is just around the corner.

With the new season on the horizon, it’s time to get into my picks for some of the NFL regular season leader markets, including passing yards leader, most passing touchdowns and most receptions recorded. Let’s break down the odds for each futures market before getting into our best bets.

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NFL Regular Season Passing Yards Leader Odds

Joe Burrow +450
Dak Prescott +800
Patrick Mahomes +1000
Baker Mayfield +1200
Jared Goff +1200
Brock Purdy +1300
CJ Stroud +1400
Josh Allen +1600
Jordan Love +2000

NFL Regular Season Passing Yards Leader Best Bet: Dak Prescott (+800)

While Joe Burrow is understandably the favourite in this market, I’m more inclined to back Dak Prescott to lead the NFL in passing yards this upcoming season. After a tremendous 2023 campaign, Prescott is a prime candidate for a bounce-back season after suffering a hamstring injury that sidelined him for a lot of last year.

There are plenty of reasons to target Prescott in this market. For starters, the Cowboys should be a pass-heavy offence and the quarterback will have CeeDee Lamb and George Pickens to throw to, along with Jake Ferguson at the tight end spot. Dallas also has major defensive concerns, so it’s likely that the Cowboys will end up in a number of shootouts this season.

With those factors in mind, Prescott should throw the ball as much (if not more) than any other quarterback in the league. Let’s take the Dallas signal-caller to lead the NFL in passing yards at +800 odds.

NFL Most Regular Season Passing Touchdowns Odds

Joe Burrow +550
Jared Goff +900
Lamar Jackson +900
Patrick Mahomes +1000
Baker Mayfield +1000
Josh Allen +1400
Dak Prescott +1500
CJ Stroud +2500
JJ McCarthy +2500
Caleb Williams +2500

NFL Most Regular Season Passing Touchdowns Best Bet: Joe Burrow (+550)

Joe Burrow is not only one of the favourites for the MVP award, but he’s also the favourite in the regular season passing touchdown market, and for good reason. After all, the Bengals’ offence should be one of the best units in football once again with the duo of Ja’Marr Chase and Tee Higgins patrolling the field at wide receiver, and Cincinnati will need to score plenty of points given its woeful defence on the other side.

Compared to the likes of Jared Goff, Lamar Jackson and a few of the other favourites in this market, Burrow is more likely to finish drives with passing touchdowns given the offensive philosophy of the Bengals compared to Detroit or Baltimore, for example. In 2024, the Bengals signal-caller threw for 43 touchdowns and it’s certainly possible that he can replicate that total this season.

NFL Most Regular Season Receptions Odds

Ja’Marr Chase +700
CeeDee Lamb +800
Amon-Ra St. Brown +900
Puka Nacua +1000
Brock Bowers +1100
Justin Jefferson +1200
Malik Nabers +1200
Brian Thomas Jr. +1500
Drake London +1500
Trey McBride +1500

NFL Most Regular Season Receptions Best Bet: CeeDee Lamb (+800)

As mentioned when making the case for Dak Prescott to lead the league in passing yards, CeeDee Lamb is going to be the dominant pass-catcher on a Cowboys team that is going to throw the ball 40+ times a game and will consistently need to play from behind thanks to their very poor defence. Lamb has consistently been one of the leading receivers in the NFL when healthy, and given the chemistry that he and Prescott have, we can expect the top Dallas wideout to pick up plenty of receptions this fall.