Israel Adesanya vs. Joe Pyfer odds and UFC Fight Night prediction

While this main event is not a title fight, a win for Adesanya could set him up as the next Welterweight challenger, while a Pfyer win could put him on the map.

Israel Adesanya vs. Joe Pyfer UFC odds

At the time of writing this preview, Adesanya’s money line is priced at -158, while Pyfer has odds of +124.

Additional betting markets would also suggest that this fight will end inside the distance, as this has odds of -148, while backing the fight to go the distance has odds of +116.

For a more specific bet, such as method of victory, backing Adesanya to win by decision carries odds of +160, while backing Pfyer to win by decision has odds of +300.

Israel Adesanya

Adesanya enters this fight with an MMA record of 24-5 and 13-5 in the UFC. His most recent UFC fight was a loss against Nassourdine Imavov by KO/TKO back in February 2025, which was his third loss in a row.

Adesanya broke into the UFC back in 2018 and has since been known as a pure striker. He averages 4.02 significant strikes per minute and has a striking accuracy of 48%. In terms of his grappling, there isn’t much to say. Adesanya averages just 0.05 takedowns every 15 minutes, has a takedown accuracy of 11%, and a takedown defence of 76%.

Joe Pyfer

Pyfer enters this fight with an MMA record of 15-3 and 7-2 in the UFC. He most recently fought in the UFC back in October 2025, where he beat Abus Magomedov by submission and won his third fight in a row. 

Pfyer has been fighting in the UFC since 2020, and unlike Adesanya, has employed more of a balanced fighting style. He averages 3.47 significant strikes per minute and has a striking accuracy of 43%. 

In comparison, his grappling is also solid, averaging 1.23 takedowns every 15 minutes and 1.0 submission attempts during the same period.

UFC Fight Night 271 Prediction: Who Will Win Adesanya vs. Pyfer?

One of the common denominators between these two fighters is that a large number of their fights end by finish. Adesanya has seen 19 of his 20 career MMA fights end inside the distance, which includes four of his last five UFC fights. 

As for Pyfer, he has seen 15 of his 18 career MMA fights end inside the distance, which includes seven of his nine UFC fights. I expect those trends to continue at UFC Fight Night 271.