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Manchester United vs. Liverpool: Premier League odds, score prediction

The English Premier League’s matchday 35 showcases a classic rivalry between the old-time, top-flight clubs of Manchester United and Liverpool. United defends their honour at Old Trafford along with their third-place spot, while Liverpool looks to usurp their position from fourth. With both teams fully focused on the domestic league, get ready for kickoff this Sunday at 10:30 AM ET.

Manchester United vs. Liverpool betting

This competition stems back to 1906, with Manchester United claiming 81 victories to Liverpool’s 67 in all competitions. United has been dominant in the last five meetings since 2024, winning two matches – including the most recent 2-1 victory in October – and drawing two others. It’s been three years since this fixture has gone scoreless or seen less than a total of three goals bulge the net.

United are your +130 moneyline favourites here on the Premier League soccer odds board considering their 17-10-7 record, as the slight +185 away underdogs of Liverpool have three more losses than the Red Devils. A draw is never out of contention, priced at +280 for this one, with the under 3.5 likely at -160.

Manchester United

United are realistically looking for a third-place finish and Champions League qualification, as their only chance of winning the League would be if they win out while both Arsenal and Man City lose all their remaining games. The Red Devils currently boast a two-game win streak and three wins in their last five games, while averaging just one goal against per game in their last three. Now at home turf against their Red rivals, it’ll take some heavy focus and offensive composure for United to find the back of the net and add to their goal tally of 60 this season.

Of United’s 60 goals, five separate players boast eight or more, including Matteus Cuhna, Bruno Fernandes, Bryan Mbeumo, Casemiro and team-leader Benjamin Sesko with 10 to his name. Sesko leads the anytime goalscoring probability for this matchup at +180, while Mbeumo (+225), Fernandes (+270), Casemiro (+350) and Cunha (+310) follow close behind.

Liverpool

Arne Slot’s squad has entered a three-game win streak in the EPL since the team’s tournament troubles in FA Cup and Champions League. While their domestic games haven’t been against harsh competition, the Reds came out of their last three with a goal differential of +5. Both sides have similar metrics, but where Liverpool struggled this season was in beating weaker teams, hence their three-point deficit from an abundance of unnecessary losses. However, they’ll be riding on high morale after a 2-1 win in the Merseyside derby against Everton on April 19, before extending their streak with a convincing 3-1 win over Palace last weekend. One major thing to consider, though, is the absences of both Mohamad Salah and top goalscorer Hugo Ekikite after both players suffered injuries that may prevent them from returning this season.

With two of their most dangerous players missing, Alexander Isak (+205) will need to continue his scoring streak after netting his third of the season against Palace. Cody Gakpo is expected to score at +295 after scoring six goals so far, with only Dominik Szoboszlai – the fourth-highest team goalscorer with five under his belt – priced at +425 for this rivalry.

Score prediction: Who will win Manchester United vs. Liverpool?

With Liverpool’s injuries plaguing them, and Manchester United performing very well at home this season despite their recent loss to Leeds on April 13, it’s looking like United will have the upper hand. The Red Devils defeated Chelsea, Aston Villa, Arsenal and Manchester City all this year, and if Carrick’s side can stay composed and avoid red cards (two in their last four games), all should go according to plan.

A draw is certainly on the table, but given the current state of Liverpool, the Man United money line looks to be a good choice in what could be a 2-1 win.