Portugal vs. Spain Round of 16 Prediction: FIFA World Cup Odds, Betting Picks
The 2010 World Cup and 2024 Euros winners of Spain take on the 2016 Euros winners of Portugal, as Cristiano Ronaldo’s team looks to make its last stand against Lamine Yamal’s ever-so-talented squad. Only one will move on to the quarterfinals, but it figures to be one of the most exciting World Cup games thus far.
Just 16 teams remain, so tune in to the epic kickoff between these massive footballing giants at 3 p.m. ET this Monday.
Check out our full list of live 2026 World Cup betting odds.
Portugal vs. Spain FIFA World Cup: How to Watch and Match Info
- July 6, 3 p.m. ET at Dallas Stadium, Arlington, Texas
- Streaming on TSN, TSN+.
- Forecast in the area indicates 33°C temperatures, 51 per cent humidity, and possible thunderstorms with 65 per cent precipitation. The game will be indoors.
Portugal vs. Spain Betting Odds
Spain come into this one as the -220 favourites to move forward against their European counterparts of Portugal, who are priced at +175 to advance. A draw within 90 minutes is plausible, set for +260 odds, with an under 2.5 and over 2.5 goals marked dead even at a -110 priceline.
Portugal vs. Spain Predicted Starting XI Lineups
Spain predicted starting XI (4-1-2-3):
— Alex Baena (LW) – Mikel Oyarzabal (CF) – Lamine Yamal (RW) —
Pedri (CM) – Dani Olmo (CM)
Rodri (CDM)
Marc Cucarella (LB) – Aymeric Laporte (CB) – Pau Cubarsí (CB) – Pedro Porro (RB)
— Unai Simón (GK) —
Spain are one of two teams left (including Mexico) that have yet to allow a goal. They may have drawn the first group stage match against Cape Verde, but they have carried out their game plans brilliantly, especially with their 4-1-2-3 formation that has continuously exhausted their opponents through possession. Nothing is expected to change from their match against Austria.
Portugal predicted starting XI (4-2-3-1):
— Cristiano Ronaldo (CF) —
Rapha Leão (LM) – Bruno Fernandes (CAM) – Pedro Neto (RM)
Vitinha (CDM) – João Neves (CDM)
Nuno Mendes (LB) – Renato Veiga (CB) – Ruben Dias (CB) – João Cancelo (RB)
— Diogo Costa (GK) —
Portugal had a very close call with Croatia in the Round of 32, and while they ultimately came out on top, they haven’t dominated the last two matches against strong opponents. Rapha Leão, who started against Croatia, made a slight difference on the left flank due to his pace, so he’s likely to start again. Expect Portugal to roll out the same 4-2-3-1 lineup for this one.
Portugal FIFA World Cup Odds and News
Portugal narrowly escaped a potential extra time after Croatia scored in the 90+10′ to equalize the game at 2-2, but the goal was called back due to offside. When facing tough adversity, Portugal appear to have issues with sealing the game early on, which could be detrimental to their knockout round performance. However, they’ve still scored eight goals to this point while only allowing two in two separate games.
Ronaldo will be highly optimistic for this one after scoring a PK opener, which will have a positive impact on the rest of the team. The Real Madrid legend enters this matchup at +180 to score anytime.
Spain FIFA World Cup Odds and News
The Spanish side’s goal differential grows even larger as they have yet to be scored on, with the team netting eight goals in their last three straight games as well as shutouts in all four of their group stage and knockout round matches. While Nico Williams will likely be unavailable due to an abductor injury, Spain seem hardly worried. They have plenty of other options, including Alex Baena — who has scored one goal so far this tournament.
Mikel Oryarzabal leads the team with four goals to his name so far, and he has been the perfect target man up front for Spain — as he comes into this match at +115 odds to score. Lamine Yamal will be hungry to be amongst the Golden Boot contenders, as he’s priced to score anytime in this one at +175.
Portugal vs. Spain Player Odds and Props
The fired-up, 18-year-old Barcelona winger won’t settle for just one goal this tournament and is likely to step up for a big moment to earn his second in this World Cup.
Manchester United’s focal point may not have scored in this tournament yet, but he’s more than capable, with his ability to provide for his teammates after earning one assist already. Expect the Portuguese centre-midfielder to either score or assist in this one.
FIFA World Cup 2026 Bracket and Futures
- Odds to advance – Spain (-220), Portugal (+175),
- Odds to win the World Cup – Spain (+560), Portugal (+1300)
Portugal vs. Spain Score Prediction
The Spanish side is absolutely lethal with their interplay, and Portugal will definitely have to see out an unorthodox game plan — as this will likely be their second match where they don’t see the majority of possession. The biggest challenge will be breaking down the Spanish back line, as no team has been able to do so yet. When it comes to depth off the bench, both sides have exceptional midfield and forward options, although Spain takes the edge with better defensive talent with options like Eric Garcia and Marcos Llorente on deck.
This clash will be extremely close, so expect a 1-1 scoreline to push the game to extra time, where the Spaniards will outclass the Portuguese with the game-winner before penalty kicks are necessary.