NFL Point Spreads Week 4: Best Picks Against the Spread

Ricky Rothstein | Updated Sep 25, 2017


Week 3 of the NFL season was very unpredictable with several underdogs winning outright. What will Week 4 bring? Here’s a quick look at all the matchups with Sports Interaction NFL odds. Games Sunday unless noted.

Chicago Bears at Green Bay Packers, Thursday

The NFL’s oldest rivalry is renewed. It’s the 12th straight season the NFC North rivals will meet in a prime-time game. The Packers have won seven of the last nine meetings at Lambeau Field. It was 26-10 in Week 7 last season, also a Thursday night game. Chicago and Green Bay enter off home wins over Pittsburgh and Cincinnati, respectively.

Point spread: Packers -7 Pick ATS: Green Bay

New Orleans Saints at Miami Dolphins

This game has a 9:30 a.m. ET kickoff from Wembley Stadium in London – the Dolphins are officially the home team. The Dolphins laid a giant egg in Week 3, losing 20-6 at the Jets. Miami only avoided a shutout on the final play of the game. New Orleans was one of those underdog winners, surprising Carolina in Charlotte.

Point spread: Saints -2.5 Pick ATS: Miami

Buffalo Bills at Atlanta Falcons

Buffalo was a home dog in Week 3 against Denver but won 26-16 despite just 21 yards rushing on 14 carries from LeSean McCoy. Tyrod Taylor threw two TD passes and had only six incompletions against one of the NFL’s top defenses. No Super Bowl Loser’s Curse yet for the Falcons as they are 3-0 after winning in Detroit on Sunday.

Point spread: Falcons -8 Pick ATS: Atlanta

Cincinnati Bengals at Cleveland Browns

Both these teams are 0-3, so at least the winner here will have temporary state bragging rights. Cincinnati blew a 21-7 third-quarter lead in an overtime loss to Green Bay on Sunday. That was the team’s first game since embattled coach Marvin Lewis changed offensive coordinators. The Browns scored a season-high 28 points but still lost at Indianapolis by three.

Point spread: Bengals -3 Pick ATS: Cincinnati

Los Angeles Rams at Dallas Cowboys

Short week for the Cowboys as they visited Arizona on Monday night. The Rams already are halfway to their 2017 win total, improving to 2-1 with a 41-39 win at San Francisco last Thursday night. Jared Goff threw for three scores and Todd Gurley ran for two and caught one TD. Last year, it would often take the Rams a few weeks to score 41 combined points.

Point spread: Cowboys -8.5 Pick ATS: LA Rams

Detroit Lions at Minnesota Vikings

Detroit scored the winning touchdown late in Sunday’s game against Atlanta – only it didn’t. Replay overturned the go-ahead score in the final seconds. Minnesota played a second straight game without injured starting QB Sam Bradford, who might return here. The Vikings didn’t miss him much Sunday in a 34-17 win over Tampa Bay. Journeyman Case Keenum had perhaps the game of his career with 369 yards passing and three scores.

Point spread: TBA (due to Bradford) Pick ATS: TBA

Carolina Panthers at New England Patriots

This almost was the Super Bowl matchup two seasons ago, but New England came up short in the final seconds of the AFC title game in Denver. The Patriots are fortunate to not be 1-2 as Tom Brady led a late comeback Sunday to avoid a huge upset vs. Houston. He threw for five scores. Carolina suffered its first loss, upset at home by New Orleans.

Point spread: Patriots -9 Pick ATS: Carolina

Jacksonville Jaguars at New York Jets

So much for the Jets going 0-16 as some experts around the league predicted. They upset the visiting Dolphins 20-6 on Sunday. The defense held Miami to 225 yards, while Josh McCown was an efficient 18-for-23 for 249 yards and a TD. Jacksonville blew out Baltimore in London but opted to not take its bye week after as many teams do. The Jags didn’t want it this early in the season.

Point spread: Jaguars -3.5 Pick ATS: Jacksonville

Pittsburgh Steelers at Baltimore Ravens

These teams simply don’t like each other even if the rivalry isn’t quite as heated as it was when the Ravens had Ray Lewis and Ed Reed. Baltimore was crushed 44-7 on Sunday in London but also opted not to take its bye week this early. Pittsburgh was upset 23-17 in overtime at Chicago. These teams split last year, each winning at home. Their games are almost always close.

Point spread: Steelers -2.5 Pick ATS: Pittsburgh

Tennessee Titans at Houston Texans

The Titans are tied for the AFC South lead after beating visiting Seattle 33-27. DeMarco Murray was in question to play with a hamstring injury but did and rushed for 115 yards and a TD. If there’s such a thing as a good loss, Houston had one in falling 36-33 in New England. Rookie Deshaun Watson showed what he’s capable of in throwing for 301 yards and two scores. Tennessee and Houston split last year, each winning at home.

Point spread: Titans -1 Pick ATS: Houston

San Francisco 49ers at Arizona Cardinals

Arizona is on a short week after hosting Dallas on Monday. The 49ers are on extra rest following a 41-39 home loss to the Rams last Thursday. That was progress considering San Francisco entered that game having failed to score a touchdown the first two weeks. Arizona swept the Niners last year.

Point spread: Cardinals -7 Pick ATS: San Francisco

Philadelphia Eagles at Los Angeles Chargers

The Eagles had the most dramatic win of Week 3 as Jake Elliott hit a 61-yard field goal as time expired to beat the New York Giants. That’s the longest game-winner in NFL history for a rookie kicker. Elliott is only on the team because usual kicker Caleb Sturgis in hurt. The Chargers lost 24-10 to Kansas City to remain winless.

Point spread: Chargers -1 Pick ATS: LA Chargers

New York Giants at Tampa Bay Buccaneers

The Giants ended a streak of eight straight games scoring 20 points or fewer on Sunday but still came up short in Philadelphia, 27-24. The pressure keeps mounting on Coach Ben McAdoo. The Bucs were manhandled at the Vikings, 34-17. Jameis Winston was picked off three times.

Point spread: Bucs -3.5 Pick ATS: Tampa Bay

Oakland Raiders at Denver Broncos

Denver was upset 26-16 in Buffalo on Sunday, looking like a completely different team than the one that crushed Dallas the previous Sunday. The Raiders were outclassed Sunday night at Washington, 27-10. They had a scant 128 yards of offense. These teams split last season, each winning at home. QB Derek Carr missed Oakland’s Week 17 loss with an injury.

Point spread: Broncos -2 Pick ATS: Denver

Indianapolis Colts at Seattle Seahawks

The Sunday night game. The Colts probably saved the job of Coach Chuck Pagano with their 31-28 home win over Cleveland. Indy was again without starting quarterback Andrew Luck, and he’s not playing here, either. Seattle is 0-2 on the road following Sunday’s 33-27 defeat at Tennessee. Russell Wilson threw for 373 yards and four scores in a losing effort.

Point spread: Seahawks -13.5 Pick ATS: Indianapolis

Washington Redskins at Kansas City Chiefs, Monday

Kansas City is still perfect following a 24-10 victory at the Chargers. Kareem Hunt continued a stellar start to his career with 172 yards rushing and a TD on 17 carries. He’s your early NFL Offensive Rookie of the Year leader. Washington dominated Oakland’s high-powered offense in a 27-10 win Sunday night as the Raiders totaled seven first downs. Skins QB Kirk Cousins was 25-for-30 for 365 yards and three scores, nearly a perfect rating.

Point spread: Chiefs -7 Pick ATS: Kansas City