2025 CFL Week 12 Picks and Betting Odds: West Division powerhouses face off in Calgary
We’re nearing the point of no return for teams at the bottom of the standings, so we could see some desperate football throughout this week’s schedule.
We’ve gone through all the info, so let’s try to mine some solid picks out of all four Week 12 games.
Make sure to check out Sports Interaction’s complete list of CFL game odds, CFL futures and CFL specials and props.

Winnipeg Blue Bombers at Montreal Alouettes
Week 12 of the 2025 CFL season kicks off in Montreal as the injury-plagued Alouettes play host to the Winnipeg Blue Bombers.
It’s been an absolute disaster for Montreal over the last few weeks. The Als are riding a three-game losing streak that has also seen them lose three quarterbacks to injury. Starter Davis Alexander (hamstring) and backup McLeod Bethel-Thompson (elbow) are both on the six-game injured list, while third-stringer Caleb Evans (ACL) is done for the season. That leaves a quarterback room of James Morgan, Cameron Dukes (signed on Aug. 13) and Shea Patterson (signed this week).
Winnipeg hasn’t had the injury troubles Montreal is dealing with, but the Bombers have had some bad luck when closing out games. In Week 10, Winnipeg blew a 17-point lead in a loss to Calgary, while last week they gave up another 17-point lead against Ottawa, relying on a late Sergio Castillo field goal to salvage a win.
I’m high on the Bombers this week for obvious reasons as the Alouettes are relying on their fourth quarterback in four weeks. This could be a blowout.
Pick: Winnipeg -6
Edmonton Elks at Ottawa RedBlacks
A pair of three-win teams meet in the nation’s capital on Friday night, with the Edmonton Elks travelling to face the Ottawa RedBlacks.
Edmonton has been playing better football lately, recording back-to-back wins over Toronto and Montreal, with quarterback Cody Fajardo playing a major role. Over the last four weeks, Fajardo has a 77.2 per cent completion rate while throwing for 1,165 yards with six touchdowns and just two interceptions.
The big question with the RedBlacks right now is at quarterback. Dru Brown left last week’s loss in Winnipeg with a lower-body injury and head coach Bob Dyce has said it’s unlikely he plays on Friday. That means Dustin Crum will take the reins. Crum has a 62.4 per cent completion rate this season, while throwing for 625 yards with two touchdowns. He’s added another 199 yards and six touchdowns on the ground.
This is a must-win game for both teams’ playoff chances. I think Edmonton has a huge advantage, however, as they have a quarterback trending in the right direction and Ottawa will likely struggle to produce points with Crum at the helm.
Pick: Edmonton -3.5, Under 53.5
BC Lions at Toronto Argonauts
It’s a double-header on Saturday, with the first game from BMO Field as the Argonauts try to end a three-game skid when they host the BC Lions.
Toronto officially boasts the worst record in the CFL at 2-8 following last week’s disappointing loss in Edmonton. The Argos are dead last in the CFL in most major statistics such as points allowed and rushing yards for/against. To make matters worse, it looks like quarterback Chad Kelly isn’t close to returning from the fractured leg he suffered in last year’s East Final.
BC, on the other hand, is trending upwards. The Lions’ offence has been electric in recent weeks, scoring at least 27 points in five straight games. A lot of the credit has to go to quarterback Nathan Rourke, who has passed for 790 yards with six touchdowns and two interceptions over the Leos’ current two-game win streak.
Nick Arbuckle has done a fine job subbing in as Toronto’s starting quarterback, but fine won’t be good enough to match an offence as hot as the Lions.
Pick: BC -3.5
Saskatchewan Roughriders at Calgary Stampeders
The final game of the week is nearly a pick’em between the league’s top two teams, with Saskatchewan Roughriders visiting the Calgary Stampeders.
As if anyone needed reminding, the 8-1 Roughriders continued to separate themselves from the rest of the league over the last two weeks, with a 34-6 win in Montreal and a 29-9 home drubbing of Hamilton. Saskatchewan tops the CFL in offensive points, points allowed, net offence allowed, sacks and just about every other major statistic. Oh, and they have one of the favourites for Most Outstanding Player in quarterback Trevor Harris.
The 6-3 Stamps should feel good this week as the only team to beat Saskatchewan this season, 24-10 in Week 6. Vernon Adams Jr. went off for 428 passing yards and three touchdowns in that game, while Dedrick Mills had 85 rushing yards. Calgary’s 134 rushing yards were the most the Riders have given up this season as they have allowed an average of just 61 rushing yards allowed in their other eight games.
This is the toughest game of the week to predict. Was Calgarys Week 6 win over Saskatchewan a blip for the Riders, or do the Stamps have this team figured out? I lean more towards this being a redemption game for Saskatchewan, who will need to focus on stopping the run.
Pick: Saskatchewan +1
