Edmonton Oilers vs. Vegas Golden Knights Prediction, NHL Odds

Payton Matthews | Updated Oct 22, 2021

Can the undefeated Edmonton Oilers stay perfect in Vegas against the Golden Knights?

October 22, 2021, 10:00 PM ET
T-Mobile Arena
Puckline +1.5 -213
Moneyline +100
Over / Under o +6.5


Betting Action


Puckline -1.5 +177
Moneyline -120
Over / Under u +6.5


Betting Action


For the first time this season, the unbeaten Edmonton Oilers will play the second of a back-to-back as they visit the Vegas Golden Knights on Friday.

The Knights are -140 favourites to win on the NHL odds, with a total of 6.5.

Oilers vs. Golden Knights NHL Betting Odds

It’s the first of four regular-season meeting between the Oilers and Golden Knights with Edmonton returning to Vegas on Nov. 27 and the Knights at the Oilers on Jan. 14 and April 16.

Edmonton and Vegas are Pacific Division rivals, but they were in separate division last season due to the pandemic reshuffling. In 2019-20, the Knights won two of three meetings. They are 4-2 all-time at home in the series. Oilers superstar Connor McDavid has seven goals and eight assists in 10 games against Vegas. Leon Draisaitl three goals and 10 assists in 11 games but is minus-1.

Could tonight be the second career NHL start for Edmonton’s Stuart Skinner? The 2017 third-round pick started once last season vs. Ottawa and got the win despite allowing five goals on 33 shots.

The under is 4-0 in the past four meetings overall.

Edmonton Oilers

When Oilers No. 1 goaltender Mike Smith landed on injured reserve earlier this week, the team called up Stuart Skinner from the minors to back up Mikko Koskinen until Smith is back. It’s fairly rare for goaltenders these days to play both ends of a back-to-back – it does happen, though – and thus it’s possible Skinner starts because Koskinen did Thursday in a 5-1 win at Arizona. However, it wasn’t a high-tension game for Koskinen with Edmonton dominating and with the team off after this until Wednesday, I would guess he starts.

Connor McDavid had two goals and an assist Friday to reach 200 career goals. He did so in 411 games, fourth-fastest in team history. Obviously, Wayne Gretzky did it the quickest (242 games). Former Toronto Maple Leaf Zach Hyman also had two goals and is up to three on the season. The Oilers’ special teams units were great as they were 2-for-2 on the power play, had a short-handed goal and killed off all four Arizona penalties. The Oilers are 14-9 in their past 19 in the second of a back-to-back.

Vegas Golden Knights

Vegas is without its two best offensive players in former Montreal Canadien Max Pacioretty and former Ottawa Senator Mark Stone due to injury – both are week-to-week, but Pacioretty is likely to miss a handful of them with a fractured foot. Another top forward, Mattias Janmark, had been COVID protocols but was activated Thursday. Doesn’t mean he will play yet. Alex Tuch is on long-term injured reserve.

Vegas did get three reinforcements back from injury Wednesday in forwards Nicolas Roy, William Carrier and Brett Howden making their regular-season debuts. However, the Knights lost 3-1 at home to St. Louis. William Karlsson had the lone goal, his first of the year. New No. 1 netminder Robin Lehner allowed two goals to fall to 1-2-0 with a 3.41 GAA. Blueliner Alec Martinez left injured and his status is TBA. Vegas is 1-5 in its past six playing on one day of rest.

NHL Prediction: Who Will Win Oilers vs. Golden Knights?