The Tennessee Titans have proven to be the best of a bad AFC South bunch through the first four games of the season – but their problems pale in comparison to those of their division rivals from Jacksonville. The Jaguars host the Titans on Sunday afternoon in what amounts to a must-win game for a Jacksonville team that is not only off to a rough start on the field, but is also dealing with plenty of controversy surrounding first-year head coach Urban Meyer.

NFL Point Spread and Betting Analysis

Tennessee is set to take advantage of some unwanted turmoil in Jacksonville, and oddsmakers like their chances. But the Titans have been in this situation plenty over the past couple of seasons and have disappointed bettors, going just 4-2 SU and 1-5 ATS in their last six games as a road fave. And as you might expect, Sports Interaction bettors are disregarding that stretch completely, with 86 percent taking the visitors to cover.

Things are much closer to even on the totals side of the betting ledger, with a 54-46 split among Sports Interaction participants in favour of the O48.5 at -110. The sides averaged a combined 52 points in their two meetings last season, and are 7-4 O/U in their previous 11 head-to-head meetings overall. Tennessee has also been straight fire on road Overs, with an incredible 8-1 mark in their last nine games away from Nissan Stadium.

Tennessee Titans

Coming off a humbling 27-24 loss to the New York Jets last time out, the Titans should have at least one of their offensive heavy hitters back in action. Wide receiver A.J. Brown missed the Week 4 defeat with a hamstring injury but is back practicing in full and is expected to take the field this weekend. The same can’t be said for fellow wideout Julio Jones, who missed practice Wednesday and Thursday and is a major question mark for Sunday.

Jacksonville Jaguars

Bettors have been eagerly firing up their Meyer “First Coach to Be Fired” bets for a while now. But that action has no doubt intensified after Meyer came under fire earlier this week – first, for inappropriate behavior in an Ohio club, and then for not flying back with the team following a Thursday night loss to the Cincinnati Bengals. Meyer has been linked with several collegiate coaching vacancies or opportunities – and a loss this week might only stoke those flames.

NFL Prediction: Who Will Win Titans vs. Jaguars?