Saints vs. Seahawks Point Spread: NFL Week 7 Odds, Prediction

Payton Matthews | Updated Oct 19, 2021

With Russell Wilson out for at least the next few weeks, can Geno Smith do enough under centre to keep Seattle alive in the playoff hunt?

October 25, 2021, 8:15 PM ET
CenturyLink Field
Pointspread -6 -110
Moneyline -250
Over / Under o +42.5


Betting Action


Pointspread +6 -110
Moneyline +207
Over / Under u +42.5


Betting Action


It’s near-desperation time for the Seattle Seahawks as the 2-4 club remains without star QB Russell Wilson on Monday night against the visiting New Orleans Saints to conclude NFL Week 7.

The Saints 4.5-point favourites to win on the NFL odds, with a total of 43.5.

NFL Point Spread and Betting Analysis

For the past several years, Saints-Seahawks would have been a marquee matchup of future Hall of Fame quarterbacks in New Orleans’ Drew Brees and Seattle’s Russell Wilson, but of course Brees retired this off-season and Wilson is out until at least Week 10 with a finger injury.

Seattle has never finished with a losing record since drafting Wilson in 2012 but that’s definitely in play now with the club at 2-4 and an underdog Monday. It could be this is Wilson’s final season with the team as he nearly forced his way out this summer.

The all-time series between the Saints and Seahawks is tied 8-8 including playoffs. The teams last played in 2019 and New Orleans won 33-27 in Seattle in Week 3. Brees was out injured that day and Teddy Bridgewater (now with Denver) threw for two scores. Alvin Kamara rushed for one and caught a TD. Wilson threw for 406 yards and two touchdowns and rushed for two. Tyler Lockett had 11 catches for 154 yards and a TD.

The underdog is 4-1 against the spread in the past five meetings.

New Orleans Saints

The Saints come out of their bye at 3-2 and second in the NFC South. It’s hard to get a read on this team considering it has won impressively over Green Bay and New England but lost to Carolina and the New York Giants. Coach Sean Payton isn’t asking new starting QB Jameis Winston to throw all that much with 116 attempts in five games. He’s completing 60.3 per cent for 12 TDs and three picks. Winston has yet to have star receiver Michael Thomas, the former NFL Offensive Player of the Year, due to injury but he’s available to come off injured reserve this week. Alas, it doesn’t sound like Thomas is ready yet off ankle surgery.

A whopping eight starters have missed most of the season already. Pro Bowl kicker Wil Lutz is also eligible to be activated and is expected to be. The team needs Lutz as the two kickers it has used thus far are 1-for-4 on field goals and also have missed two extra points. A handful of other injured starters also are likely to return. The Saints are 17-7 ATS in their past 24 as road favourites.

Seattle Seahawks

QB Russell Wilson missed the first start of his career last Sunday night and Seattle lost 23-20 in overtime at Pittsburgh. Journeyman Geno Smith wasn’t bad in throwing for 209 yards and a TD, but he fumbled on a sack in overtime that led to the winning field goal – although it was hardly Smith’s fault. With Smith, Seattle just doesn’t have a deep downfield passing game. WR Tyler Lockett, who had a huge start to this season with Wilson, had just two catches for 35 yards. Seattle did reach out to Cam Newton but apparently didn’t think it was a fit.

Running back Alex Collins, starting for the injured Chris Carson, had 101 yards and a TD on 20 carries but suffered an injury and is in question. Fellow running back and former first-round pick Rashaad Penny (calf) will be activated from injured reserve this week and might be thrown right into the featured role. Seattle’s defence continues to rank last in the league in allowing 433.2 yards per game but was better vs. Pittsburgh. The Seahawks are 13-5 ATS in their past 18 as underdogs.

NFL Prediction: Who Will Win Saints vs. Seahawks?