Chiefs vs. Eagles Point Spread: NFL Week 4 Odds, Prediction

Andrew Rogers | Updated Sep 30, 2021


Could it be that the vaunted Chiefs are finally coming back to Earth? Oddsmakers aren’t buying it as the Chiefs look to return to the .500 mark Sunday in Philadelphia.

October 03, 2021, 1:00 PM ET
Lincoln Financial Field
Pointspread -7.5 +100
Moneyline -368
Over / Under o +54


Betting Action


Pointspread +7.5 -120
Moneyline +301
Over / Under u +54


Betting Action


Though the defending AFC champions have dropped two of their first three games to start the 2021 season, they’re still favoured by a converted touchdown on the road against an Eagles side that has dropped two in a row since winning its season opener.

NFL Point Spread and Betting Analysis

The betting public is squarely on board with the scuffling Chiefs, taking them at a whopping 91 percent clip on Sports Interaction. But things haven’t been great for Kansas City when it comes to being a road fave: it’s just 0-5-1 ATS in its last six games in that situation, including two straight outright losses coming into the weekend. The Eagles were home underdogs of 7+ points twice last season, and went 1-1 SU and 2-0 ATS in those contests.

Nearly two-thirds of Sports Interaction bettors are leaning toward the O54.5 (-110), not scared off in the least by one of the highest totals on the Week 4 board. The Eagles have converted the Over in six straight home games as underdogs of seven or more points, though just two of those games have taken place within the past 15 years. More relevant to this week, the Chiefs are 5-2 O/U in their last seven as a road fave, with five of those games producing 59+ points.

Kansas City Chiefs

Patrick Mahomes has the Chiefs offence humming along as usual, but there are big problems on the defensive side of the ball – and with division rivals Las Vegas and Denver opening 3-0, the Chiefs can ill afford to continue their struggles there. Kansas City is allowing the second-most rushing yards per game (160.3) and ranks third-last in total yards allowed (430.0); they’ve also permitted opponents to score TDs on 92.3 percent of their red-zone trips.

Philadelphia Eagles

New Eagles head coach Nick Sirianni is already under fire for his interesting game plan in last week’s 41-21 loss to the Dallas Cowboys. The Eagles had just three planned run plays in the game, a major departure for a team that is averaging an incredible 5.4 yards per carry through the first three weeks. Look for much more involvement from No. 1 running back Miles Sanders, who saw just two carries in Week 3 after getting 28 through the first two games.

NFL Prediction: Who Will Win Chiefs vs. Eagles?