Chiefs vs. Chargers Point Spread: NFL Week 2 Odds, Prediction

Sports Interaction Staff | Updated Sep 16, 2020

Clyde Edwards-Helaire, Chiefs

The Chiefs went run-heavy against the Texans in Week 1 with rookie running back Clyde Edwards-Helaire running for 138 yards and a touchdown. Will they have a similar game plan for the Chargers?

September 20, 2020, 4:25 PM ET
SoFi Stadium
Pointspread -9 -130
Moneyline -450
Over / Under o +47


Betting Action


Pointspread +9 +108
Moneyline +364
Over / Under u +47


Betting Action


Both teams kicked off Week 1 the right way and are 1-0 heading into this game, but the Chargers will have their hands full when they play their first home game at the new SoFi Stadium against the defending Super Bowl champion Kansas City Chiefs.

Pat Mahomes’ Chiefs are nine-point favourites on the NFL odds with a total of 47.5.

NFL Point Spread and Betting Analysis

The Chiefs swept both games against the Chargers last season, picking up a 24-17 home win in November and a 31-21 road win in December.  The December game clinched a first-round playoff bye for the Chiefs with Mecole Hardman returning a kickoff for a 104-yard touchdown.

The Chargers went 2-5 against the spread versus the AFC West last year, including 0-2 against the Chiefs.  Kansas City went 6-0 straight up against the AFC West last year and 5-0-1 ATS.

The Chiefs went run-heavy against the Texans in Week 1 with rookie running back Clyde Edwards-Helaire running for 138 yards and a touchdown.  If they get up early on the Chargers, Andy Reid might lean toward protecting Mahomes and going for the run-game again.  The Chiefs are 7-0-1 ATS in their last eight games following a SU win.  The Chargers offense struggled against the Bengals in Week 1 with Tyrod Taylor held to 208 passing yards and no touchdowns.  The under is now 4-0 in the Chargers’ last four September games.

Kansas City Chiefs

The Chiefs come into this game with nine days rest after a 34-20 Week 1 win against the Texans, a game in which the normally pass-heavy offense handed the ball off to rookie running back Edwards-Helaire 25 times for 138 rushing yards and a touchdown.  Even with Andy Reid riding the hot rookie, Mahomes still managed to throw for 211 yards and three touchdowns with a 75 per cent completion rate.  With Reid trying to utilize a better balance between the run-game and his superstar quarterback’s ability, could we see him continue to give Mahomes a lighter load in Week 2 and keep the ball in Edwards-Heaire’s hands?

Los Angeles Chargers

The Chargers D-line chased Bengals rookie quarterback Joe Burrow in Week 1, with Joey Bosa and Melvin Ingram III big factors in keeping Burrow at 23-for-36 passing.  LA elected to give their own rookie quarterback, Justin Herbert, more time to learn and started Tyrod Taylor, who was 16-for-30 with 208 passing yards.  After walking away from Philip Rivers in the off-season, Herbert is the quarterback of the future for the Chargers.  The main question is how long LA can last with Taylor, before their hand is forced to put the rookie quarterback in?

Who Will Win Chiefs vs. Chargers?