Los Angeles Lakers vs. San Antonio Spurs Prediction, NBA Odds

Daniel Coyle | Updated Nov 25, 2022

The San Antonio Spurs will be searching for their first straight up victory in seven games when they host the road-challenged Los Angeles Lakers in Black Friday NBA action.

L.A. Lakers
November 25, 2022, 8:00 PM ET
AT&T Center
San Antonio
Pointspread -4 -110
Moneyline -174
Over / Under o +235


Betting Action


Pointspread +4 -110
Moneyline +145
Over / Under u +235


Betting Action


The Spurs opened their current three-game home stand on Wednesday with a crushing 129-110 loss to New Orleans, and have now been outpaced by wide double-digit margin in five of their six recent defeats. The Lakers are coming off a 115-105 loss in Phoenix on Wednesday night to remain winless in six road dates so far this season.

The Lakers have faded to 3.5-point favourites since opening as 4.5-point road chalk, but maintain the support of 67% of sports bettors. The total is on the rise since opening at 228, vaulting to 232.

Lakers vs. Spurs NBA Betting Odds

Friday night’s matchup marks the first of two games involving these teams this weekend at AT&T Center, and the second of four scheduled clashes this season between these Western Conference rivals. The Lakers marched to a one-sided 123-92 win when they hosted the Spurs last Sunday, ending a two-game slide in head-to-head action. The Lakers have also won five of six in San Antonio while averaging 113.8 points per game over that stretch. However, with the Spurs scoring 107 or fewer points on four occasions, the UNDER has paid out five times in their past six home dates with LA.

Los Angeles Lakers

Winners of three straight to close out their recent home stand, the Lakers were riding high as they opened their current three-game junket in the desert, but were quickly brought back down to the Earth by the Suns, who overcame a two-point halftime deficit to hand LA its seventh loss by double-digit margins so far this season. Wednesday’s defeat extends what has been a brutal run for the Lakers on the road, where they have fallen to defeat by an average margin of 13.3 points during a 0-6 start to the season, and have now lost 23 of 26 away contests since last January. Once again, the team was without LeBron James, who has now missed five straight games with a lower body injury, and remains questionable for Friday’s contest. And once again, Anthony Davis carried this team on his back, piling up 37 points and a season-high 21 boards to extend a run of five straight double-doubles in which he has averaged 33.2 points and 17.4 boards per game. Davis has also averaged 34.5 points and 14 boards in his past two visits to San Antonio.

San Antonio Spurs

The Spurs once again fell flight in their return home on Wednesday night, spotting the Pelicans an early double-digit lead while tallying just 19 points in the opening frame. That extends a dismal run that has seen this team average just 19.5 first-quarter points over their past two outings, and just 24 points in the first 12 minutes during their 0-6 slide. Overall, the Spurs have failed to crack the century mark in points three times during their current slide, fueling a dismal 1-5 against the run, and have also covered just twice during a 0-5 run as home underdogs. The silver lining for the Spurs comes in the form of Devin Vassell, who once again led the squad with 26 points in Wednesday’s loss. Vassell now leads the Spurs with 20.6 points per game and has averaged 23.2 points over his past five outings. Jakob Poeltl has also been steady under the bucket. The big man recorded 14 rebounds on Wednesday, and has averaged 15.4 points and 10.3 boards over his past seven appearances.

NBA Prediction: Who Will Win Lakers vs. Spurs?